军事战斗与中年男性亚临床动脉粥样硬化负担：ARIC 研究。
Military combat and burden of subclinical atherosclerosis in middle aged men: the ARIC study.
机构信息
Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27514, USA.
出版信息
Prev Med. 2010 May-Jun;50(5-6):277-81. doi: 10.1016/j.ypmed.2010.02.009. Epub 2010 Feb 23.
BACKGROUND
Studies of the cardiovascular consequences of combat stress are few and inconclusive.
OBJECTIVE
The association between combat exposure and subclinical atherosclerosis at Atherosclerosis Risk in Communities (ARIC) Study visits 1 (1987-1989) and 2 (1990-1992) was assessed among 5347 men from four U.S. communities.
METHODS
Measured an average of 36 years after military entry, carotid intima-media thickness (CIMT) and carotid plaque among non-combat veterans (n=2127) were compared with non-veterans (n=2042) and veterans reporting combat experience (n=1178).
RESULTS
Compared to non-combat veterans, non-veterans (risk difference (RD): 10.61; 95% confidence interval (CI): 0.81, 20.41) and combat veterans (RD: 12.79; 95% CI: 0.72, 24.86) had higher age-adjusted mean CIMT. Differences remained for combat veterans after adjustment for race, father's education and age at service entry but not years of service and for non-veterans after adjustment for race but not father's education. No differences in carotid plaque were noted.
CONCLUSION
Results do not suggest that combat has a long-term detrimental effect on subclinical atherosclerosis among men.
背景
关于战斗应激对心血管影响的研究很少且结果不一致。
目的
在动脉粥样硬化风险社区（ARIC）研究的第 1 次（1987-1989 年）和第 2 次（1990-1992 年）访视中，评估了四项美国社区 5347 名男性中战斗暴露与亚临床动脉粥样硬化之间的关系。
方法
在平均入伍后 36 年时，比较了非退役军人（n=2127）、退役军人（n=2042）和报告有战斗经历的退役军人（n=1178）的颈动脉内膜中层厚度（CIMT）和颈动脉斑块。
结果
与非退役军人相比，退役军人（风险差异（RD）：10.61；95%置信区间（CI）：0.81，20.41）和退役军人（RD：12.79；95% CI：0.72，24.86）的平均 CIMT 更高。在调整种族、父亲的教育程度和服役时的年龄后，战斗退役军人的差异仍然存在，但在调整服役年限和年龄后，差异不再存在。在调整种族后，非退役军人的差异仍然存在，但在调整父亲的教育程度后，差异不再存在。颈动脉斑块没有差异。
结论
结果表明，战斗对男性亚临床动脉粥样硬化没有长期的不利影响。
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