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芬兰退伍军人 TAMRISK 研究 28 年随访结果显示,老年冠心病死亡率。

Late-life coronary heart disease mortality of Finnish war veterans in the TAMRISK study, a 28-year follow-up.

机构信息

Department of Medical Biochemistry, University of Tampere Medical School, Tampere, Finland.

出版信息

BMC Public Health. 2011 Feb 1;11(1):71. doi: 10.1186/1471-2458-11-71.

Abstract

BACKGROUND

Wartime stress has been associated with increased late-life mortality of all causes of death. We evaluated whether wounded Finnish World War II veterans who were alive at the age of 55 have increased long-term coronary heart disease (CHD) mortality.

METHODS

Health survey data were recorded in 1980 from 667 men, aged 55 years. Of them 102 had been wounded or injured in action during 1939-1945. The remaining participants served as the comparison group. The death certificates during a 28-year follow-up were obtained from the national statistics centre. Statistical comparisons were done by Cox proportional hazard regression model.

RESULTS

There were altogether 140 deaths from CHD. In men who had been wounded or injured in action the crude CHD mortality rate per 10,000 population was 2843, while in the comparison group the corresponding figure was 1961. Men who had been wounded or injured in action were 1.7 times (95% CI 1.1-2.5; p = 0.01) more likely to die from CHD than the comparison group.

CONCLUSIONS

Physical trauma at young adulthood may extend to lifelong effects on health. This study suggests that being physically wounded or injured in war may lead to increased CHD mortality in late adulthood in a Finnish population.

摘要

背景

战时压力与各种原因导致的老年死亡率增加有关。我们评估了在 55 岁时仍在世的芬兰二战参战老兵是否存在长期冠心病(CHD)死亡率增加的情况。

方法

1980 年,对 667 名年龄为 55 岁的男性进行了健康调查。其中 102 人在 1939-1945 年期间因战受伤。其余参与者作为对照组。在 28 年的随访期间,从国家统计中心获得了死亡证明。通过 Cox 比例风险回归模型进行统计比较。

结果

共有 140 人死于 CHD。在因战受伤的男性中,每 10,000 人中有 2843 人死于 CHD,而对照组的相应数字为 1961。因战受伤的男性死于 CHD 的可能性是对照组的 1.7 倍(95%CI 1.1-2.5;p = 0.01)。

结论

青年时期的身体创伤可能会对健康产生终身影响。本研究表明,在芬兰人群中,年轻时因战受伤可能会导致晚年 CHD 死亡率增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c97/3038159/41202673c320/1471-2458-11-71-1.jpg

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