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Interleukin-28b: a key piece of the hepatitis C virus recovery puzzle.

作者信息

Thio Chloe L, Thomas David L

出版信息

Gastroenterology. 2010 Apr;138(4):1240-3. doi: 10.1053/j.gastro.2010.02.033. Epub 2010 Feb 23.

DOI:10.1053/j.gastro.2010.02.033
PMID:20184973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3805379/
Abstract
摘要

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本文引用的文献

1
Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.大规模候选基因分析丙型肝炎病毒的自发清除。
J Infect Dis. 2010 May 1;201(9):1371-80. doi: 10.1086/651606.
2
Prioritizing GWAS results: A review of statistical methods and recommendations for their application.优先考虑 GWAS 结果：统计方法综述及其应用建议。
Am J Hum Genet. 2010 Jan;86(1):6-22. doi: 10.1016/j.ajhg.2009.11.017.
3
Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.
白细胞介素28B基因多态性单核苷酸多态性rs8099917的GG基因型与人类嗜T淋巴细胞病毒1型（HTLV-1）携带者的HTLV-1相关脊髓病/热带痉挛性截瘫（HAM/TSP）有关。
PLoS Negl Trop Dis. 2014 Sep 18;8(9):e3199. doi: 10.1371/journal.pntd.0003199. eCollection 2014 Sep.
4
Mechanisms of HCV-induced liver cancer: what did we learn from in vitro and animal studies?HCV 诱导肝癌的机制：我们从体外和动物研究中学到了什么？
Cancer Lett. 2014 Apr 10;345(2):210-5. doi: 10.1016/j.canlet.2013.06.028. Epub 2013 Jul 18.
5
Association of two polymorphisms of the IL28B gene with viral factors and treatment response in 1,518 patients infected with hepatitis C virus.在 1518 例丙型肝炎病毒感染患者中，IL28B 基因的两个多态性与病毒因素和治疗反应相关联。
J Gastroenterol. 2012 May;47(5):596-605. doi: 10.1007/s00535-012-0531-1. Epub 2012 Mar 23.
6
IL28B alleles exert an additive dose effect when applied to HCV-HIV coinfected persons undergoing peginterferon and ribavirin therapy.IL28B 等位基因在接受聚乙二醇干扰素和利巴韦林治疗的 HCV-HIV 合并感染患者中表现出相加的剂量效应。
PLoS One. 2011;6(10):e25753. doi: 10.1371/journal.pone.0025753. Epub 2011 Oct 7.
7
Simultaneous genotyping of rs12979860 and rs8099917 variants near the IL28B locus associated with HCV clearance and treatment response.同时检测与 HCV 清除和治疗反应相关的 IL28B 基因座附近的 rs12979860 和 rs8099917 变异的基因型。
J Mol Diagn. 2011 Jul;13(4):446-51. doi: 10.1016/j.jmoldx.2011.03.008. Epub 2011 May 14.
8
Pharmacodynamics of PEG-IFN-[alpha]-2a and HCV response as a function of IL28B polymorphism in HIV/HCV-coinfected patients.聚乙二醇干扰素-α-2a 的药效学及 IL28B 多态性对 HIV/HCV 共感染患者 HCV 应答的影响。
J Acquir Immune Defic Syndr. 2011 Feb 1;56(2):95-9. doi: 10.1097/QAI.0b013e3182020596.
9
IL28B and the control of hepatitis C virus infection.IL28B 与丙型肝炎病毒感染的控制。
Gastroenterology. 2010 Dec;139(6):1865-76. doi: 10.1053/j.gastro.2010.10.004. Epub 2010 Oct 13.
IL28B 基因变异与慢性丙型肝炎及治疗失败相关：一项全基因组关联研究。
Gastroenterology. 2010 Apr;138(4):1338-45, 1345.e1-7. doi: 10.1053/j.gastro.2009.12.056. Epub 2010 Jan 11.
4
ISG15, a ubiquitin-like interferon-stimulated gene, promotes hepatitis C virus production in vitro: implications for chronic infection and response to treatment.ISG15，一种泛素样干扰素刺激基因，促进丙型肝炎病毒在体外的产生：对慢性感染和治疗反应的影响。
J Gen Virol. 2010 Feb;91(Pt 2):382-8. doi: 10.1099/vir.0.015388-0. Epub 2009 Oct 21.
5
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus.白细胞介素28B的基因变异与丙型肝炎病毒的自发清除
Nature. 2009 Oct 8;461(7265):798-801. doi: 10.1038/nature08463.
6
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy.IL28B与慢性丙型肝炎α干扰素和利巴韦林治疗的反应相关。
Nat Genet. 2009 Oct;41(10):1100-4. doi: 10.1038/ng.447. Epub 2009 Sep 13.
7
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C.IL28B全基因组与聚乙二醇化干扰素-α和利巴韦林治疗慢性丙型肝炎疗效的关联研究
Nat Genet. 2009 Oct;41(10):1105-9. doi: 10.1038/ng.449. Epub 2009 Sep 13.
8
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.白细胞介素28B的基因变异可预测丙型肝炎治疗诱导的病毒清除情况。
Nature. 2009 Sep 17;461(7262):399-401. doi: 10.1038/nature08309. Epub 2009 Aug 16.
9
Interferon-lambda is functionally an interferon but structurally related to the interleukin-10 family.干扰素-λ在功能上是一种干扰素，但在结构上与白细胞介素-10家族相关。
J Biol Chem. 2009 Jul 31;284(31):20869-75. doi: 10.1074/jbc.M109.002923. Epub 2009 May 20.
10
Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.在丙型肝炎抗病毒长期治疗对抗肝硬化试验中，干扰素-α 通路基因变异与聚乙二醇化干扰素-α2a 联合利巴韦林治疗慢性丙型肝炎病毒感染的疗效
Hepatology. 2009 Jun;49(6):1847-58. doi: 10.1002/hep.22877.