Interleukin-28b: a key piece of the hepatitis C virus recovery puzzle.
作者信息
Thio Chloe L, Thomas David L
出版信息
Gastroenterology. 2010 Apr;138(4):1240-3. doi: 10.1053/j.gastro.2010.02.033. Epub 2010 Feb 23.
Abstract
摘要
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本文引用的文献
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Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus.大规模候选基因分析丙型肝炎病毒的自发清除。
J Infect Dis. 2010 May 1;201(9):1371-80. doi: 10.1086/651606.
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Prioritizing GWAS results: A review of statistical methods and recommendations for their application.优先考虑 GWAS 结果：统计方法综述及其应用建议。
Am J Hum Genet. 2010 Jan;86(1):6-22. doi: 10.1016/j.ajhg.2009.11.017.
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Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.IL28B 基因变异与慢性丙型肝炎及治疗失败相关：一项全基因组关联研究。
Gastroenterology. 2010 Apr;138(4):1338-45, 1345.e1-7. doi: 10.1053/j.gastro.2009.12.056. Epub 2010 Jan 11.
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ISG15, a ubiquitin-like interferon-stimulated gene, promotes hepatitis C virus production in vitro: implications for chronic infection and response to treatment.ISG15，一种泛素样干扰素刺激基因，促进丙型肝炎病毒在体外的产生：对慢性感染和治疗反应的影响。
J Gen Virol. 2010 Feb;91(Pt 2):382-8. doi: 10.1099/vir.0.015388-0. Epub 2009 Oct 21.
5
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus.白细胞介素28B的基因变异与丙型肝炎病毒的自发清除
Nature. 2009 Oct 8;461(7265):798-801. doi: 10.1038/nature08463.
6
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy.IL28B与慢性丙型肝炎α干扰素和利巴韦林治疗的反应相关。
Nat Genet. 2009 Oct;41(10):1100-4. doi: 10.1038/ng.447. Epub 2009 Sep 13.
7
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C.IL28B全基因组与聚乙二醇化干扰素-α和利巴韦林治疗慢性丙型肝炎疗效的关联研究
Nat Genet. 2009 Oct;41(10):1105-9. doi: 10.1038/ng.449. Epub 2009 Sep 13.
8
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.白细胞介素28B的基因变异可预测丙型肝炎治疗诱导的病毒清除情况。
Nature. 2009 Sep 17;461(7262):399-401. doi: 10.1038/nature08309. Epub 2009 Aug 16.
9
Interferon-lambda is functionally an interferon but structurally related to the interleukin-10 family.干扰素-λ在功能上是一种干扰素，但在结构上与白细胞介素-10家族相关。
J Biol Chem. 2009 Jul 31;284(31):20869-75. doi: 10.1074/jbc.M109.002923. Epub 2009 May 20.
10
Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.在丙型肝炎抗病毒长期治疗对抗肝硬化试验中，干扰素-α 通路基因变异与聚乙二醇化干扰素-α2a 联合利巴韦林治疗慢性丙型肝炎病毒感染的疗效
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