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拔管1周后危重症患者的经口摄入量是否充足

Adequacy of oral intake in critically ill patients 1 week after extubation.

作者信息

Peterson Sarah J, Tsai Annalisa A, Scala Celina M, Sowa Diane C, Sheean Patricia M, Braunschweig Carol L

机构信息

Rush University Medical Center, Chicago, IL 60612, USA.

出版信息

J Am Diet Assoc. 2010 Mar;110(3):427-33. doi: 10.1016/j.jada.2009.11.020.

Abstract

Hospital malnutrition is associated with increased morbidity and mortality, particularly among patients admitted to intensive care units (ICUs). The purpose of this observational study (August to November 2007) was to examine the adequacy of oral intake and to identify predictors of oral intake after ICU patients were removed from invasive mechanical ventilation. Patients aged > or = 18 years who required mechanical ventilation for at least 24 hours, advanced to an oral diet postextubation, and did not require supplemental enteral or parenteral nutrition were included. The first 7 days of oral intake after extubation were assessed via modified multiple-pass 24-hour recall and the numbers of days on therapeutic diets and reasons for decreased intake were collected. Oral intake <75% of daily requirements was considered inadequate. Descriptive statistics, chi2, Student t tests, and logistic regression analyses were conducted. Of the 64 patients who met eligibility criteria, 50 were included. Of these 50 patients, 54% were women and intubated for 5.2 days, with a mean age of 59.1 years, body mass index of 28.7, and Acute Physiology and Chronic Health Evaluation II score of 21.9. Subjective Global Assessment determined 44% were malnourished upon admission to the ICU. The average daily energy and protein intake failed to exceed 50% of daily requirements on all 7 days for the entire population. The majority of patients who consumed <75% of daily requirements were prescribed a therapeutic diet and/or identified "no appetite" and nausea/vomiting as the barriers to eating. Although more research is needed, these data call into question the use of restrictive oral diets and suggest that alternative medical nutrition therapies are needed to optimize nutrient intake in this unique patient population.

摘要

医院营养不良与发病率和死亡率增加相关,尤其是在入住重症监护病房(ICU)的患者中。这项观察性研究(2007年8月至11月)的目的是检查经口摄入量是否充足,并确定ICU患者撤掉创 伤性机械通气后经口摄入量的预测因素。纳入年龄≥18岁、需要机械通气至少24小时、拔管后过渡到经口饮食且不需要补充肠内或肠外营养的患者。通过改良的多次24小时回顾法评估拔管后经口摄入的前7天,并收集接受治疗性饮食的天数及摄入量减少的原因。经口摄入量<每日需求量的75%被认为不足。进行了描述性统计、卡方检验、学生t检验和逻辑回归分析。在符合纳入标准的64例患者中,50例被纳入研究。在这50例患者中,54%为女性,插管时间为5.2天,平均年龄59.1岁,体重指数28.7,急性生理与慢性健康状况评分II为21.9。主观全面评定法确定44%的患者在入住ICU时即存在营养不良。整个人群在全部7天的平均每日能量和蛋白质摄入量均未超过每日需求量的50%。大多数经口摄入量<每日需求量75%的患者接受了治疗性饮食,和/或认为“没有食欲”以及恶心/呕吐是进食的障碍。尽管还需要更多研究,但这些数据对限制经口饮食的使用提出了质疑,并表明需要采用替代的医学营养疗法来优化这一特殊患者群体的营养摄入。

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