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[一名2岁眼睑横纹肌肉瘤患儿的病例报告]

[Case report of a 2-year-old child with palpebral rhabdomyosarcoma].

作者信息

Bonnin N, Nezzar H, Viennet A, Barthelemy I, Demeocq F, Gabrillargues J, Dauplat M-M, Bacin F

机构信息

Service d'ophtalmologie, Hôpital Gabriel Montpied, CHU Clermont-Ferrand, Clermont-Ferrand.

出版信息

J Fr Ophtalmol. 2010 Mar;33(3):178-84. doi: 10.1016/j.jfo.2010.01.011. Epub 2010 Feb 24.

Abstract

Rhabdomyosarcoma is an extremely virulent rare tumor whose early diagnosis considerably improves survival and visual prognosis. We report the case of a 2-year-old child with levator palpebrae superioris muscle rhabdomyosarcoma revealed by a sudden and isolated blepharoptosis. Initially, clinical and imaging investigations did not show any abnormality but a painful tumor with some hematoma quickly developed, so the investigations were repeated. The CT-scan showed an extra-conal tumor that had developed at the superior part of the orbit. Histology confirmed the diagnosis of embryonic rhabdomyosarcoma. Because of its results, treatment consisting of chemotherapy associating ifosfamide, vincristine, actinomycin and orbital radiotherapy of 40 Gy with a local addition of 10 Gy were administrated with successful results after a 3-year-follow-up.

摘要

横纹肌肉瘤是一种极具侵袭性的罕见肿瘤,早期诊断可显著提高生存率和视力预后。我们报告了一例2岁儿童因突然出现的孤立性上睑下垂而被诊断为提上睑肌横纹肌肉瘤的病例。最初,临床和影像学检查未发现任何异常,但很快出现了一个伴有一些血肿的疼痛性肿瘤,于是再次进行检查。CT扫描显示眶锥外肿瘤位于眼眶上部。组织学检查确诊为胚胎性横纹肌肉瘤。鉴于检查结果,给予了由异环磷酰胺、长春新碱、放线菌素联合化疗以及40 Gy的眼眶放疗并局部追加10 Gy的治疗方案,3年随访后取得了成功的治疗效果。

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