安非他酮用于治疗神经性疼痛。
Bupropion for the treatment of neuropathic pain.
作者信息
Shah Tanmay H, Moradimehr Abdolali
机构信息
East Tennessee State University, Quillen College of Medicine, Johnson City, TN, USA.
出版信息
Am J Hosp Palliat Care. 2010 Aug;27(5):333-6. doi: 10.1177/1049909110361229. Epub 2010 Feb 24.
PMID:20185402
Abstract
Neuropathic pain is a common problem in clinical practice, affecting patients physically, emotionally, financially, and socially. Current treatment includes antidepressants, antiepileptics, and opioid analgesics. Bupropion is a specific inhibitor of neuronal noradrenaline reuptake and a weak inhibitor of dopamine reuptake, which shows some promise in the treatment of neuropathic pain.
摘要
神经性疼痛是临床实践中的常见问题，在身体、情感、经济和社交方面影响着患者。目前的治疗方法包括使用抗抑郁药、抗癫痫药和阿片类镇痛药。安非他酮是一种特异性的去甲肾上腺素再摄取抑制剂，也是一种较弱的多巴胺再摄取抑制剂，在神经性疼痛的治疗中显示出一定前景。
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