Diagnostic value of plasma antidiuretic hormone, electrocochleography, and glycerol test in patients with endolymphatic hydrops.

OBJECTIVE

To investigate the relationship between the plasma antidiuretic hormone (p-ADH) level, electrocochleogram (ECoG), and the glycerol test in patients with endolymphatic hydrops (ELH).

PATIENTS AND METHODS

The subjects were 60 patients, including 51 with Ménière's disease (except for cochlear Ménière's disease), 7 with delayed ELH, and 2 with syphilitic ELH. The time period for measurements of the p-ADH level, ECoG and the glycerol test was within 4 weeks.

RESULTS

13 patients showed positive results for all tests. 58 patients showed positive results for at least one of three tests. Only 2 patients showed negative results for all tests.

CONCLUSION

The p-ADH level, ECoG and the glycerol test show different selectivity of ELH detection. It is useful to perform all three tests to diagnose ELH.