Fukuoka Hisakuni, Takumi Yutaka, Tsukada Keita, Miyagawa Maiko, Oguchi Tomohiro, Ueda Hitoshi, Kadoya Masumi, Usami Shin-ichi
Department of Otorhinolaryngology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Japan.
Acta Otolaryngol. 2012 Feb;132(2):141-5. doi: 10.3109/00016489.2011.635383. Epub 2011 Dec 27.
3 T MRI after intratympanic injection of gadolinium-based contrast agent (GBCA) is more useful for the diagnosis of endolymphatic hydrops compared with the glycerol test and electrocochleography (ECoG).
To investigate the relationship between 3 T MRI after intratympanic injection of GBCA, the glycerol test, and ECoG in patients with Meniere's disease (MD).
A total of 20 patients with MD were evaluated. Diluted gadodiamide (a gadolinium-based contrast agent) was administered to the bilateral tympanic cavity by injection through the tympanic membrane. After 24 h, the endolymphatic hydrops was evaluated by a 3.0 T MR scanner. To investigate cochlear hydrops, the glycerol test and ECoG were carried out in all patients.
A positive result was observed in 11 patients (55%) in the glycerol test and in 12 patients (60%) by ECoG. The incidence of positive findings when evaluating the same patients with both the glycerol test and ECoG increased to 75%. Nineteen of 20 (95%) patients showed positive results for 3 T MRI.
与甘油试验和电耳蜗图（ECoG）相比，鼓室内注射钆基造影剂（GBCA）后的3T磁共振成像（MRI）对诊断内淋巴积水更有用。
研究梅尼埃病（MD）患者鼓室内注射GBCA后的3T MRI、甘油试验和ECoG之间的关系。
共评估了20例MD患者。通过鼓膜穿刺向双侧鼓室注射稀释的钆双胺（一种钆基造影剂）。24小时后，用3.0T MR扫描仪评估内淋巴积水情况。为研究耳蜗积水，对所有患者进行了甘油试验和ECoG检查。
甘油试验中有11例患者（55%）结果为阳性，ECoG检查中有12例患者（60%）结果为阳性。用甘油试验和ECoG对同一患者进行评估时，阳性结果的发生率增至75%。20例患者中有19例（95%）3T MRI结果为阳性。
