鼓室内注射钆布醇后3T磁共振成像、耳蜗电图及甘油试验对梅尼埃病患者的诊断价值比较
Comparison of the diagnostic value of 3 T MRI after intratympanic injection of GBCA, electrocochleography, and the glycerol test in patients with Meniere's disease.
作者信息
Fukuoka Hisakuni, Takumi Yutaka, Tsukada Keita, Miyagawa Maiko, Oguchi Tomohiro, Ueda Hitoshi, Kadoya Masumi, Usami Shin-ichi
机构信息
Department of Otorhinolaryngology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Japan.
出版信息
Acta Otolaryngol. 2012 Feb;132(2):141-5. doi: 10.3109/00016489.2011.635383. Epub 2011 Dec 27.
CONCLUSION
3 T MRI after intratympanic injection of gadolinium-based contrast agent (GBCA) is more useful for the diagnosis of endolymphatic hydrops compared with the glycerol test and electrocochleography (ECoG).
OBJECTIVE
To investigate the relationship between 3 T MRI after intratympanic injection of GBCA, the glycerol test, and ECoG in patients with Meniere's disease (MD).
METHODS
A total of 20 patients with MD were evaluated. Diluted gadodiamide (a gadolinium-based contrast agent) was administered to the bilateral tympanic cavity by injection through the tympanic membrane. After 24 h, the endolymphatic hydrops was evaluated by a 3.0 T MR scanner. To investigate cochlear hydrops, the glycerol test and ECoG were carried out in all patients.
RESULTS
A positive result was observed in 11 patients (55%) in the glycerol test and in 12 patients (60%) by ECoG. The incidence of positive findings when evaluating the same patients with both the glycerol test and ECoG increased to 75%. Nineteen of 20 (95%) patients showed positive results for 3 T MRI.
结论
与甘油试验和电耳蜗图（ECoG）相比，鼓室内注射钆基造影剂（GBCA）后的3T磁共振成像（MRI）对诊断内淋巴积水更有用。
目的
研究梅尼埃病（MD）患者鼓室内注射GBCA后的3T MRI、甘油试验和ECoG之间的关系。
方法
共评估了20例MD患者。通过鼓膜穿刺向双侧鼓室注射稀释的钆双胺（一种钆基造影剂）。24小时后，用3.0T MR扫描仪评估内淋巴积水情况。为研究耳蜗积水，对所有患者进行了甘油试验和ECoG检查。
结果
甘油试验中有11例患者（55%）结果为阳性，ECoG检查中有12例患者（60%）结果为阳性。用甘油试验和ECoG对同一患者进行评估时，阳性结果的发生率增至75%。20例患者中有19例（95%）3T MRI结果为阳性。
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