Merrell Stephen C, Rahbar Reza, Alomari Ahmad I, Padua Horacio M, Vargas Sara O, Neufeld Ellis J, Dearden Jennifer L, Mulliken John B, Greene Arin K
Department of Plastic Surgery, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA.
J Craniofac Surg. 2010 Mar;21(2):422-6. doi: 10.1097/SCS.0b013e3181cfa777.
A 5-day-old male neonate was referred to our vascular anomalies center with a large cystic submandibular mass. History and physical examination and ultrasonographic results indicated the diagnosis to be macrocystic lymphatic malformation. Consequently, the child was treated with sclerotherapy and subtotal excision. The histopathological examination result showed that the lesion was infantile myofibroma. This diagnostic error was attributed to atypical features of infantile myofibroma in this child: unusually large cysts, rapid enlargement, and coagulopathy. This report expands the clinical spectrum of infantile myofibromatosis and suggests its consideration in the differential diagnosis of neonatal cystic cervicofacial lesions.
一名5天大的男婴因下颌下巨大囊性肿块被转诊至我们的血管异常中心。病史、体格检查及超声检查结果提示诊断为大囊型淋巴管畸形。因此，该患儿接受了硬化治疗及次全切除术。组织病理学检查结果显示病变为婴儿肌纤维瘤。这一诊断错误归因于该患儿婴儿肌纤维瘤的非典型特征：囊肿异常大、迅速增大及凝血病。本报告拓展了婴儿肌纤维瘤病的临床谱，并建议在新生儿囊性颈面部病变的鉴别诊断中考虑该病。
