Thennavan Aatish, Narayanaswamy Venkadasalapathi, Niazi Thanvir Mohammed, Rao Lakshmi, Radhakrishnan Raghu
Department of Oral and Maxillofacial Pathology, Manipal College of Dental Sciences, Manipal University, Manipal 576104, India.
Case Rep Pediatr. 2012;2012:630804. doi: 10.1155/2012/630804. Epub 2012 Aug 27.
Infantile myofibroma is a rare and benign tumour of children presenting in the head and neck region. Rendering a final diagnosis of infantile myofibroma can be challenging in the light of nonspecific clinical, radiological findings and its histopathological similarities with a number of neoplasms especially spindle cell tumours. In this paper we discuss a case of infantile myofibroma in a 2-month-old infant, enumerating the various differential entities that have to be eliminated in reaching its specific diagnosis and highlighting the importance of immunopositivity to vimentin and smooth muscle actin (SMA) in establishing its myofibroblastic differentiation.
婴儿肌纤维瘤是一种罕见的儿童良性肿瘤，好发于头颈部。鉴于其非特异性的临床和影像学表现，以及与多种肿瘤尤其是梭形细胞瘤的组织病理学相似性，做出婴儿肌纤维瘤的最终诊断可能具有挑战性。在本文中，我们讨论了一例2个月大婴儿的婴儿肌纤维瘤病例，列举了在做出明确诊断时必须排除的各种鉴别诊断，并强调了波形蛋白和平滑肌肌动蛋白（SMA）免疫阳性在确定其肌成纤维细胞分化中的重要性。
