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[儿童头颈部淋巴管畸形的诊断与治疗进展]

[The diagnosis and treatment progress of lymphatic malformations of the head and neck in children].

作者信息

Wang Ying, Li Xiaoyan

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Jun;29(11):1049-52.

PMID:26536719
Abstract

Lymphatic malformations including macrocystic and microcystic malformation are congenital benign vascular disease. The incidence in children is much higher than adults and they most often occur in head and neck. There are a variety of diagnosis and treatment methods in lymphatic malformations. This paper reviewed the recent literatures with respect to the pathology, imaging and treatment of the lymphatic malformations in children. And we detailed the advantage and disadvantage of surgical excision, sclerotherapy, laser ablation and drug treatment of lymphatic malformations particularly in children. Surgical excision continues to be integral to treat in many cases when the lesions involve the eye socket or are large enough to affect breathing, but it should not be overused without consideration of the histologic types and extent. In addition, cervicofacial macrocystic lesions tend to sclerotherapy while superficial mucosal microsystic lesions are amenable to laser therapy. In order to obtain the best treatment outcomes, the treatment protocol should be individualized and comprehensive.

摘要

淋巴管畸形,包括大囊型和微囊型畸形,是一种先天性良性血管疾病。儿童发病率远高于成人,且最常发生于头颈部。淋巴管畸形有多种诊断和治疗方法。本文回顾了有关儿童淋巴管畸形的病理学、影像学及治疗的近期文献。我们详细阐述了淋巴管畸形,尤其是儿童淋巴管畸形的手术切除、硬化治疗、激光消融及药物治疗的优缺点。当病变累及眼眶或体积大到足以影响呼吸时,手术切除在许多病例中仍是治疗的重要组成部分,但不应在不考虑组织学类型和范围的情况下过度使用。此外,颈面部大囊型病变倾向于硬化治疗,而浅表黏膜微囊型病变适合激光治疗。为了获得最佳治疗效果,治疗方案应个体化且全面。

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1
[The diagnosis and treatment progress of lymphatic malformations of the head and neck in children].[儿童头颈部淋巴管畸形的诊断与治疗进展]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Jun;29(11):1049-52.
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[Management of lymphatic malformations in oral and maxillofacial regions: the rationale according to the new classification].[口腔颌面部淋巴管畸形的治疗:基于新分类的理论依据]
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Surgical excision as primary treatment modality for extensive cervicofacial lymphatic malformations in children.手术切除作为儿童广泛性头颈部淋巴管畸形的主要治疗方式。
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Treatment guidelines of lymphatic malformations of the head and neck.头颈部淋巴管畸形治疗指南。
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Current treatment paradigms in the management of lymphatic malformations.目前在淋巴管畸形管理中的治疗模式。
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Doxycycline sclerotherapy as primary treatment of head and neck lymphatic malformations in children.强力霉素硬化疗法作为儿童头颈部淋巴管畸形的主要治疗方法。
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引用本文的文献

1
A new therapy for microcystic lymphatic malformations: the combination of intralesional laser thermolysis and percutaneous sclerotherapy.微囊性淋巴管畸形的一种新疗法:病灶内激光热解与经皮硬化疗法联合应用
Front Cell Dev Biol. 2024 Dec 24;12:1490351. doi: 10.3389/fcell.2024.1490351. eCollection 2024.
2
A nomogram for predicting sclerotherapy response for treatment of lymphatic malformations in children.用于预测儿童淋巴管畸形硬化治疗反应的列线图。
Eur J Med Res. 2022 Oct 21;27(1):209. doi: 10.1186/s40001-022-00844-3.
3
From Benign to Malign in a Case of Cervical Adenopathy in a 17-Year-Old Adolescent: Diagnostic Traps.
17岁青少年宫颈腺病从良性到恶性转变的病例:诊断陷阱
Case Rep Pediatr. 2016;2016:5173849. doi: 10.1155/2016/5173849. Epub 2016 Nov 27.