Belli Evaristo, Mazzone Noemi, Rendine Guido
Department of Maxillo-Facial Surgery, II Faculty of Medicine and Surgery Sapienza University, Sant Andrea Hospital, Sapienza University of Rome, Rome, Italy.
J Craniofac Surg. 2010 Mar;21(2):387-9. doi: 10.1097/SCS.0b013e3181cfa5f6.
Osteosarcoma can develop secondary to malignant transformation within a preexisting benign bone lesion, such as Paget disease, osteonecrosis, fibrous dysplasia, and chronic infection, or it can arise in previously irradiated areas. This article presents the case of a 36-year-old woman who was affected by a radioinduced osteosarcoma after radiotherapy for an adenoid cystic carcinoma of the left parotid gland treated when she was 24 years old.