Natale Franca, La Penna Chiara, Padoa Anna, Agostini Massimo, Panei Massimo, Cervigni Mauro
Department of Urogynecology, S. Carlo-IDI Hospital, Rome, Italy.
Int Urogynecol J. 2010 May;21(5):515-22. doi: 10.1007/s00192-009-1064-x. Epub 2010 Feb 26.
Our study compared high levator myorrhaphy (HLM) and uterosacral ligament suspension (USLS) for vaginal apex fixation from both an anatomical and functional point of view, and assessed the impact of surgery on quality of life (QoL) and sexuality.
Two hundred twenty-nine patients with symptomatic stage >or=2 apical prolapse were randomized to USLS or HLM. Those patients who also needed cystocele repair additionally underwent an anterior prosthetic reinforcement. We defined as cure no prolapse of stage 2 or greater in any compartments according to the POP-Q system.
Correction of apical prolapse was observed in 96.6% of the HLM group and 98.3% of the USLS group. However, a persistent anterior wall prolapse occurred in 29.2% of the HLM group and in 35.4% of the USLS group. Both groups reported improvement in storage, voiding, and prolapse-related symptoms. Urodynamics of patients in the HLM group showed post-operative reduction in detrusor pressure at maximum flow and an increase in maximum flow. Both groups saw similar improvement in QoL. We did not encounter any serious side effects, except for nine cases of intraoperative ureteral occlusion following USLS.
This study demonstrates similar efficacy of HLM and USLS for vaginal apex suspension; however, USLS has a higher incidence of complications involving the upper urinary tract.
我们的研究从解剖学和功能学角度比较了高位提肌缝合术(HLM)和子宫骶骨韧带悬吊术(USLS)在阴道顶端固定中的应用,并评估了手术对生活质量(QoL)和性功能的影响。
229例有症状的≥2期顶端脱垂患者被随机分为USLS组或HLM组。那些还需要膀胱膨出修复的患者额外接受了前路假体加固。根据盆腔器官脱垂定量(POP-Q)系统,我们将任何腔室中无2期或更高级别脱垂定义为治愈。
HLM组96.6%的患者和USLS组98.3%的患者顶端脱垂得到矫正。然而,HLM组29.2%的患者和USLS组35.4%的患者出现持续性前壁脱垂。两组患者在储尿、排尿及脱垂相关症状方面均有改善。HLM组患者的尿动力学检查显示术后最大尿流率时逼尿肌压力降低,最大尿流率增加。两组患者的生活质量改善情况相似。除USLS术后发生9例术中输尿管梗阻外,我们未遇到任何严重的副作用。
本研究表明HLM和USLS在阴道顶端悬吊方面疗效相似;然而,USLS涉及上尿路的并发症发生率更高。