Department of Rheumatology, South Infirmary Victoria University Hospital, Cork, Ireland.
Ir J Med Sci. 2010 Jun;179(2):273-6. doi: 10.1007/s11845-010-0475-5. Epub 2010 Feb 26.
To identify cardiovascular and other comorbidities in a general rheumatology cohort.
Interviews/retrospective chart audits were conducted on 1,000 patients attending rheumatology outpatient clinics of a university teaching hospital. Comorbidities were classified using the Charlson comorbidity index (Ambrose et al. in Ir J Med Sci 178(1):53-55, 2009).
Mean age 58 +/- 15.3 years, mean BMI 26. Of the patients, 400 (40%) were diagnosed with dyslipidemia and hypertension (p = 0.002), 160 (16%) with obesity and 80 (8%) with hypothyroidism. Overall 160 (16%) patients were diagnosed with coronary heart disease (CHD). Of these, 120 (75%) had RA (p = 0.001), 100 (63%) were male, mean age 60 +/- 15.8 years, 120 (75%) had dyslipidemia and BMI > 30 (p = 0.002), 112 (70%) were smokers (p = 0.002), 40 (25%) were diagnosed with diabetes mellitus and 20 (12%) with hypothyroidism.
The increased prevalence of these comorbidities may serve as a reminder to the rheumatologists that many of their patients will have coexistent disease of which they need to be aware to properly plan their management.
在普通风湿科队列中确定心血管和其他合并症。
对一家大学教学医院的 1000 名风湿科门诊患者进行了访谈/回顾性病历审核。使用 Charlson 合并症指数（Ambrose 等人，Ir J Med Sci 178（1）：53-55，2009）对合并症进行分类。
平均年龄 58 +/- 15.3 岁，平均 BMI 为 26。在患者中，400 名（40%）被诊断为血脂异常和高血压（p = 0.002），160 名（16%）为肥胖，80 名（8%）为甲状腺功能减退。共有 160 名（16%）患者被诊断为冠心病（CHD）。其中，120 名（75%）患有类风湿关节炎（RA）（p = 0.001），100 名（63%）为男性，平均年龄 60 +/- 15.8 岁，120 名（75%）血脂异常且 BMI > 30（p = 0.002），112 名（70%）为吸烟者（p = 0.002），40 名（25%）患有糖尿病，20 名（12%）患有甲状腺功能减退。
这些合并症的患病率增加可能提醒风湿病医生，他们的许多患者将同时患有需要了解的其他疾病，以便为其管理制定适当的计划。
