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[经直肠上动脉亚甲蓝灌注评估全直肠系膜切除术后切除的系膜标本完整性]

[Integrity evaluation of resected mesentery specimen after total mesorectal excision by methylene blue perfusion via superior rectal artery].

作者信息

Lou Zheng, Zhang Wei, Mei Zu-bing, Wang Li-li, Ji Qiu-fang, Meng Rong-gui, Fu Chuan-gang

机构信息

Department of Colorectal Surgery, Changhai Hospital, The Second Military Medical University, Shanghai, China.

出版信息

Zhonghua Wei Chang Wai Ke Za Zhi. 2010 Feb;13(2):148-50.

PMID:20186629
Abstract

OBJECTIVE

To evaluate the integrity of the resected mesentery specimen after total mesorectal excision (TME) for low rectal cancer using methylene blue perfusion via the superior rectal artery.

METHODS

Twenty patients with low rectal cancer were randomly divided into the methylene blue group (n=10) and the control group (n=10). All the patients received TME and macroscopic examination of the mesorectal surface was performed to evaluate the quality of the surgical specimen. The methylene blue was injected into the specimen postoperatively via superior rectal artery.

RESULTS

The mesorectal surface of all the specimens was intact on macroscopic examination. However, after methylene blue perfusion, 2 specimens were found to be incomplete. The number of lymph nodes in the methylene blue group were significantly larger (17.3+/-2.4 vs 12.4+/-5.4, P=0.016).

CONCLUSIONS

Integrity evaluation of TME specimen is necessary. Methylene blue perfusion is a convenient and effective method to identify subtle incompleteness of specimen and can improve the detection of lymph node.

摘要

目的

通过经直肠上动脉注入亚甲蓝,评估低位直肠癌全直肠系膜切除(TME)术后切除的系膜标本的完整性。

方法

将20例低位直肠癌患者随机分为亚甲蓝组(n = 10)和对照组(n = 10)。所有患者均接受TME手术,并对直肠系膜表面进行大体检查以评估手术标本的质量。术后经直肠上动脉向标本注入亚甲蓝。

结果

所有标本的直肠系膜表面在大体检查时均完整。然而,亚甲蓝灌注后,发现2个标本不完整。亚甲蓝组的淋巴结数量明显更多(17.3±2.4对12.4±5.4,P = 0.016)。

结论

TME标本的完整性评估是必要的。亚甲蓝灌注是一种识别标本细微不完整性的便捷有效方法,可提高淋巴结的检出率。

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