Department of Heart Center, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China.
Clin Cardiol. 2010 Feb;33(2):72-6. doi: 10.1002/clc.20692.
It is currently thought that pulmonary embolism and deep vein thrombosis are different manifestations of the same pathological process of venous thromboembolism. Venous thromboembolism has a negative correlation with high-density lipoprotein cholesterol.
Pulmonary embolism has a negative correlation with the level of high-density lipoprotein cholesterol.
A total of 90 patients with pulmonary embolism, diagnosed and treated at a single center, were retrospectively analyzed for the present study. Among them were 57 cases of pulmonary arterial trunk embolism in group A and 33 cases of pulmonary arterial non-trunk embolism in group B.
The results showed that the level of high-density lipoprotein cholesterol decreased markedly in patients with pulmonary arterial trunk embolism as compared to those with pulmonary arterial non-trunk embolism. A stepwise logistic regression analysis was performed upon the relationship between pulmonary arterial trunk embolism and multiple factors. The results showed that a pulmonary arterial trunk embolism had a negative correlation with the level of high-density lipoprotein cholesterol and a positive correlation with triglyceride and high sensitivity C-reactive protein.
Pulmonary arterial trunk embolism is negatively correlated with the level of high-density lipoprotein cholesterol.
目前认为肺栓塞和深静脉血栓形成是静脉血栓栓塞症这一病理过程的不同表现。静脉血栓栓塞症与高密度脂蛋白胆固醇呈负相关。
肺栓塞与高密度脂蛋白胆固醇水平呈负相关。
本研究回顾性分析了在单中心诊断和治疗的 90 例肺栓塞患者。其中 A 组 57 例为肺动脉干栓塞，B 组 33 例为肺动脉非干栓塞。
结果显示，与肺动脉非干栓塞患者相比，肺动脉干栓塞患者的高密度脂蛋白胆固醇水平显著降低。对肺动脉干栓塞与多种因素之间的关系进行逐步逻辑回归分析。结果表明，肺动脉干栓塞与高密度脂蛋白胆固醇呈负相关，与甘油三酯和高敏 C 反应蛋白呈正相关。
肺动脉干栓塞与高密度脂蛋白胆固醇水平呈负相关。
