Head and Neck Medical Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.
J Surg Oncol. 2010 Mar 15;101(4):292-8. doi: 10.1002/jso.21438.
The strategy of induction chemotherapy prior to planned definitive local therapy for head and neck squamous cell carcinoma has been studied for over 30 years, and appears to have a role in select clinical situations. Here we review landmark studies regarding induction chemotherapy, both in the pre-taxane era and in the current taxane era, and we address some of the unresolved questions regarding the role of induction chemotherapy in head and neck cancer.
在头颈部鳞状细胞癌的计划确定性局部治疗之前进行诱导化疗的策略已经研究了 30 多年，并且在某些临床情况下似乎具有一定的作用。在这里，我们回顾了关于诱导化疗的里程碑式研究，包括在紫杉醇前时代和当前的紫杉醇时代，并解决了一些关于诱导化疗在头颈部癌症中的作用的未解决问题。
