新辅助化疗在治疗晚期上皮性卵巢癌中的作用。
The role of neoadjuvant chemotherapy in treating advanced epithelial ovarian cancer.
机构信息
Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
出版信息
J Surg Oncol. 2010 Mar 15;101(4):334-43. doi: 10.1002/jso.21482.
The current management of advanced ovarian cancer consists of aggressive primary cytoreductive surgery (PCS) followed by combination platinum based chemotherapy. Recent studies have suggested that platinum-based chemotherapy may be of benefit in patients with advanced ovarian cancer prior to cytoreductive surgery (neoadjuvant chemotherapy, NACT). The concept of NACT has not been completely validated in the treatment of ovarian cancer. This review will discuss the role of NACT in patients with advanced epithelial ovarian cancer.
目前，晚期卵巢癌的治疗方法包括积极的初次细胞减灭术（PCS）加联合铂类化疗。最近的研究表明，在进行细胞减灭术（新辅助化疗，NACT）之前，铂类化疗可能对晚期卵巢癌患者有益。NACT 在卵巢癌治疗中的作用尚未完全得到验证。本文将讨论 NACT 在晚期上皮性卵巢癌患者中的作用。
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