Kikuchi I
National Leprosarium Kikuchi Keifuen, Kumamoto-ken, Japan.
Semin Dermatol. 1991 Mar;10(1):7-11.
A case of congenital onychodysplasia of the index fingers involving the nails of both thumbs is presented, and the characteristics and various hypotheses of this most distal congenital reduction malformation are reviewed. The presence of such an atypical case as this may suggest that there is heterogeneity of this congenital condition, in agreement with Ohtsu's classification of this condition into (1) common type, (2) secondary type, and (3) hereditary type. An abnormal hand grip hypothesis, proposed by the author, could not be substantiated by Ohtsu, although it cannot be denied, for instance, based on the presence of a sucking blister. Three groups of congenital distal malformations can be differentiated by the pattern of involved fingers.
本文报告一例累及双侧拇指指甲的先天性示指甲发育异常病例，并对这种最远端先天性发育不全畸形的特征和各种假说进行了综述。出现这样一个非典型病例可能表明这种先天性疾病存在异质性，这与大津将这种疾病分为（1）普通型、（2）继发型和（3）遗传型的分类一致。作者提出的异常握力假说未得到大津的证实，不过，例如基于吸吮水疱的存在，也不能否认这一假说。根据受累手指的模式可区分出三组先天性远端畸形。
