Miura T, Nakamura R
Department of Orthopaedic Surgery, School of Medicine, Nagoya University, Japan.
J Hand Surg Am. 1990 Sep;15(5):793-7. doi: 10.1016/0363-5023(90)90159-o.
Twenty-two fingers of 13 patients had dysplastic nails. Four types of congenital onychodysplasia of the index fingers such as anonychia, rudimentary, split rudimentary (polyonychia), and micronychia were found in five, three, eight, and six fingers, respectively. Narrowing at the distal end of the affected distal phalanx (lack of the cresent-shaped cap), and a Y-shaped bony projection were characteristic features seen on x-ray films. There were no associated ectodermal abnormalities. Syndactyly was a relatively common associated hand anomaly. Some cases of congenital onychodysplasia of the index fingers were inherited. These findings suggest that impediments to the membranous ossification center can lead to a dysplastic crescent-shaped cap with nail anomalies.
13名患者的22根手指出现指甲发育异常。在食指中发现了四种先天性甲发育异常，如无甲、发育不全、分裂发育不全（多指）和小甲，分别出现在5根、3根、8根和6根手指上。X线片上可见受累远节指骨远端变窄（缺乏新月形帽）和Y形骨突起。无相关的外胚层异常。并指是一种相对常见的相关手部畸形。部分食指先天性甲发育异常病例为遗传性。这些发现表明，膜性骨化中心的障碍可导致伴有指甲异常的发育异常新月形帽。
