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结核分枝杆菌转录组。

The transcriptome of Mycobacterium tuberculosis.

机构信息

Department of Biology, Seattle University, 901 12th Ave., Seattle, WA, USA.

出版信息

Appl Microbiol Biotechnol. 2010 Mar;86(1):1-9. doi: 10.1007/s00253-009-2399-4.

DOI:10.1007/s00253-009-2399-4
PMID:20187299
Abstract

In this review, we summarize the present understanding of the Mycobacterium tuberculosis transcriptome and catalog both experimentally verified findings and computationally derived predictions. We also provide a new analysis for a range of discoveries by comparing the results of previously independent research papers. Bringing these data together and improving their accessibility should help catalyze further discoveries. This minireview also provides some general insights that may be valuable to those working to characterize the transcriptome of less-studied prokaryotes.

摘要

在这篇综述中,我们总结了目前对结核分枝杆菌转录组的理解,并对实验验证的结果和计算推导的预测进行了分类。我们还通过比较之前独立研究论文的结果,对一系列发现进行了新的分析。将这些数据汇集在一起并提高其可访问性,应该有助于进一步的发现。这篇迷你综述还提供了一些一般性的见解,对于那些致力于描述研究较少的原核生物转录组的人可能是有价值的。

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The transcriptome of Mycobacterium tuberculosis.结核分枝杆菌转录组。
Appl Microbiol Biotechnol. 2010 Mar;86(1):1-9. doi: 10.1007/s00253-009-2399-4.
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[A review of studies on differential transcriptional profile of Mycobacterium tuberculosis in vivo and in vitro].[结核分枝杆菌体内外差异转录谱研究综述]
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引用本文的文献

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REMap: Operon map of M. tuberculosis based on RNA sequence data.REMap:基于RNA序列数据的结核分枝杆菌操纵子图谱。
Tuberculosis (Edinb). 2016 Jul;99:70-80. doi: 10.1016/j.tube.2016.04.010. Epub 2016 Apr 29.
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Comparative analyses of transport proteins encoded within the genomes of Mycobacterium tuberculosis and Mycobacterium leprae.
结核分枝杆菌和麻风分枝杆菌基因组中编码的转运蛋白的比较分析。
Biochim Biophys Acta. 2012 Mar;1818(3):776-97. doi: 10.1016/j.bbamem.2011.11.015. Epub 2011 Nov 29.
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Transcriptional profiling of mycobacterium tuberculosis during infection: lessons learned.结核分枝杆菌感染期间的转录谱分析:经验教训
Front Microbiol. 2010 Nov 18;1:121. doi: 10.3389/fmicb.2010.00121. eCollection 2010.
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The impact of transcriptomics on the fight against tuberculosis: focus on biomarkers, BCG vaccination, and immunotherapy.转录组学在抗击结核病中的作用:聚焦生物标志物、卡介苗接种及免疫疗法。
Clin Dev Immunol. 2011;2011:192630. doi: 10.1155/2011/192630. Epub 2010 Dec 20.