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结核分枝杆菌转录组。

The transcriptome of Mycobacterium tuberculosis.

机构信息

Department of Biology, Seattle University, 901 12th Ave., Seattle, WA, USA.

出版信息

Appl Microbiol Biotechnol. 2010 Mar;86(1):1-9. doi: 10.1007/s00253-009-2399-4.

Abstract

In this review, we summarize the present understanding of the Mycobacterium tuberculosis transcriptome and catalog both experimentally verified findings and computationally derived predictions. We also provide a new analysis for a range of discoveries by comparing the results of previously independent research papers. Bringing these data together and improving their accessibility should help catalyze further discoveries. This minireview also provides some general insights that may be valuable to those working to characterize the transcriptome of less-studied prokaryotes.

摘要

在这篇综述中,我们总结了目前对结核分枝杆菌转录组的理解,并对实验验证的结果和计算推导的预测进行了分类。我们还通过比较之前独立研究论文的结果,对一系列发现进行了新的分析。将这些数据汇集在一起并提高其可访问性,应该有助于进一步的发现。这篇迷你综述还提供了一些一般性的见解,对于那些致力于描述研究较少的原核生物转录组的人可能是有价值的。

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