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痰培养是否会影响社区获得性肺炎的管理和/或结局?

Does sputum culture affect the management and/or outcome of community-acquired pneumonia?

机构信息

Department of Infectious Diseases, Sari University of Medical Sciences, Sari, Mazandaran, Islamic Republic of Iran.

出版信息

East Mediterr Health J. 2009 Jul-Aug;15(4):792-9.

PMID:20187530
Abstract

This prospective study was conducted in 6 hospitals in Edmonton, Canada to determine the factors associated with obtaining sputum for culture and the effect of sputum culture on the management of patients with community-acquired pneumonia (CAP). Participants were 1362 adults who were hospitalized with CAP. Sputum was obtained from 539 (39.6%) patients, of which 507 (94.1%) were good quality, acceptable for culture; 171 (33.7%) of these had a positive sputum culture. Levofloxacin, cefuroxime and azithromycin were the most common antibiotics prescribed for the groups with positive sputum culture and no sputum collection. Positive sputum culture was demonstrated in only a small number of patients with CAP; this did not affect antimicrobial therapy or mortality.

摘要

这项前瞻性研究在加拿大埃德蒙顿的 6 家医院进行,旨在确定与获取痰培养物相关的因素,以及痰培养对社区获得性肺炎 (CAP) 患者管理的影响。参与者为 1362 名因 CAP 住院的成年人。从 539 名患者(39.6%)中获取了痰标本,其中 507 名(94.1%)标本质量良好,可用于培养;其中 171 名(33.7%)培养结果阳性。对于痰培养阳性且未采集痰标本的患者,左氧氟沙星、头孢呋辛和阿奇霉素是最常用的抗生素。CAP 患者中只有少数患者的痰培养呈阳性,这并未影响抗菌治疗或死亡率。

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