Department of Oral Health Sciences, Sheikh Zayed Federal Postgraduate Medical Institute, Lahore, Pakistan.
East Mediterr Health J. 2009 Jul-Aug;15(4):1011-20.
Associations of oral diseases with noncommunicable diseases such as diabetes, cardiovascular diseases, chronic respiratory diseases, osteoporosis and chronic renal failure are widely reported in the literature from developed countries. Commonality of risk factors, changes in systemic inflammatory mediators and body metabolism play a role in this association. This paper reviews current knowledge on the burden and association of oral and systemic diseases, and highlights the paucity of information and research from the Eastern Mediterranean Region and other developing countries. A call is made for further research to understand the status and significance of oral-systemic disease associations and develop guidelines for their control in this Region.
在发达国家的文献中广泛报道了口腔疾病与非传染性疾病（如糖尿病、心血管疾病、慢性呼吸道疾病、骨质疏松症和慢性肾衰竭）之间的关联。危险因素的共同性、系统性炎症介质和身体代谢的变化在这种关联中起作用。本文综述了口腔和系统性疾病负担和关联的现有知识，并强调了来自东地中海区域和其他发展中国家的信息和研究的缺乏。呼吁进一步研究，以了解口腔-系统性疾病关联的现状和意义，并制定该区域控制这些疾病的指南。
