Paediatric Preventive Cardiology Department, Isfahan Cardiovascular Research Centre (WHO Collaborating Centre in Eastern Mediterranean Region), Isfahan University of Medical Sciences, Isfahan, Iran.
Diabetol Metab Syndr. 2010 Apr 7;2:22. doi: 10.1186/1758-5996-2-22.
Cardiovascular disease (CVD) risk factors begin from early life and track onto adulthood. Oral and dental diseases share some risk factors with CVD, therefore by finding a clear relation between dental diseases and cardiometabolic risk factors; we can then predict the potential risk of one based on the presence of the other. This study aimed to compare the prevalence of dental caries between two groups of age-matched adolescents with and without CVD risk factors.
In this case-control study, the decayed, missing and filled surfaces (DMFS), based on the criteria of the World Health Organization, were compared in two groups of equal number (n = 61 in each group) of population-based sample of adolescents with and without CVD risk factors who were matched for sex and age group.
The study participants had a median age 13 y 5 mo, age range 11 y 7 mo to 16 y 1 mo, with male-to-female proportion of 49/51. We found significant difference between the mean values of DMFS, body mass index, waist and hip circumferences, as well as serum lipid profile in the case and control groups. Significant correlations were documented for DMFS with TC (r = 0.54, p = 0.02), LDL-C (r = 0.55, p = 0.01) and TG (r = 0.52, p = 0.04) in the case group; with LDL-C (r = 0.47, p = 0.03) in the whole study participants and with TC in control s(r = 0.45, p = 0.04).
Given the significant associations between dental caries and CVD risk factors among adolescents, more attention should be paid to oral health, as one of the topics to be taken into account in primordial/primary prevention of cardiometabolic disorders.
心血管疾病（CVD）的危险因素始于生命早期，并持续到成年期。口腔和牙齿疾病与 CVD 有一些共同的危险因素，因此，如果发现牙齿疾病与心血管代谢危险因素之间存在明确的关系，我们就可以根据另一种疾病的存在来预测一种疾病的潜在风险。本研究旨在比较两组年龄匹配的青少年中 CVD 危险因素的存在与不存在的龋齿患病率。
在这项病例对照研究中，根据世界卫生组织的标准，比较了两组年龄匹配（每组 n = 61）、性别和年龄组匹配的基于人群的青少年样本中龋齿的缺失、补牙和腐烂表面（DMFS）。
研究参与者的中位年龄为 13 岁 5 个月，年龄范围为 11 岁 7 个月至 16 岁 1 个月，男女比例为 49/51。我们发现病例组和对照组之间 DMFS、体重指数、腰围和臀围以及血脂谱的平均值存在显著差异。在病例组中，DMFS 与 TC（r = 0.54，p = 0.02）、LDL-C（r = 0.55，p = 0.01）和 TG（r = 0.52，p = 0.04）呈显著相关；在整个研究参与者中与 LDL-C（r = 0.47，p = 0.03）相关，在对照组中与 TC 相关（r = 0.45，p = 0.04）。
鉴于青少年中龋齿与 CVD 危险因素之间存在显著关联，应更加关注口腔健康，将其作为预防心血管代谢紊乱的一级预防的一个考虑因素。
