Varinska L, Mirossay L, Mojzisova G, Mojzis J
Department of Pharmacology, Faculty of Medicine, P.J. Safarik University, Kosice, Slovak Republic.
Pharmazie. 2010 Jan;65(1):57-63.
Angiogenesis, the formation of new blood vessels from a preexisting vascular network is considered a key step in tumour growth, invasion, and metastasis. Recent studies show that several natural compounds inhibit angiogenesis and nowadays numerous bioactive plant compounds are tested for their antiangiogenic potential. This review examines current knowledge regarding the antiangiogenic potential of several phytochemicals, including polyphenols resveratrol and curcumin as well as miscellaneous compounds from garlic, Hypericum perforatum, Panax ginseng, Coptis chinensis and Rheum palmatum.
血管生成是指从预先存在的血管网络形成新的血管，它被认为是肿瘤生长、侵袭和转移的关键步骤。最近的研究表明，几种天然化合物可抑制血管生成，如今众多具有生物活性的植物化合物正在接受抗血管生成潜力的测试。本综述考察了有关几种植物化学物质抗血管生成潜力的现有知识，这些植物化学物质包括多酚白藜芦醇和姜黄素，以及来自大蒜、贯叶连翘、人参、黄连和掌叶大黄的其他化合物。
