Kasiotis Konstantinos M, Pratsinis Harris, Kletsas Dimitris, Haroutounian Serkos A
Benaki Phytopathological Institute, Laboratory of Pesticides Toxicology, 8 St. Delta Street, Athens, Kifissia 14561, Greece.
Food Chem Toxicol. 2013 Nov;61:112-20. doi: 10.1016/j.fct.2013.03.038. Epub 2013 Apr 6.
Dietary stilbenes comprise a class of natural compounds that display significant biological activities of medicinal interest. Among them, their antioxidant, anti-aging and anti-angiogenesic properties are well established and subjects of numerous research endeavors. This mini-review aspires to account and present the literature reports published on research concerning various natural and synthetic stilbenes, such as trans-resveratrol. Special focus was given to most recent research findings, while the mechanisms underlying their anti-aging and anti-angiogenic effects as well as the respective signaling pathways involved were also presented and discussed.
膳食芪类化合物是一类具有重要药用生物活性的天然化合物。其中,它们的抗氧化、抗衰老和抗血管生成特性已得到充分证实,也是众多研究的主题。本综述旨在阐述并呈现已发表的有关各种天然和合成芪类化合物(如反式白藜芦醇)研究的文献报道。特别关注了最新的研究发现,同时也介绍并讨论了它们抗衰老和抗血管生成作用的潜在机制以及相关的信号通路。