Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA.
J Int Neuropsychol Soc. 2010 May;16(3):401-11. doi: 10.1017/S1355617710000196. Epub 2010 Mar 1.
This study examines rates of reporting of new or worse post-traumatic symptoms for patients with a broad range of injury severity at 1 month and 1 year after traumatic brain injury (TBI), as compared with those whose injury spared the head, and assesses variables related to symptom reporting at 1 year post-injury. Seven hundred thirty two TBI subjects and 120 general trauma comparison (TC) subjects provided new or worse symptom information at 1 month and/or 1 year post-injury. Symptom reporting at 1 year post-injury was compared in subgroups based on basic demographics, preexisting conditions, and severity of brain injury. The TBI group reported significantly more symptoms at 1 month and 1 year after injury than TCs (each p < .001). Although symptom endorsement declined from 1 month to 1 year, 53% of people with TBI and 24% of TC continued to report 3 or more symptoms at 1 year post-injury. Symptom reporting in the TBI group was significantly related to age, gender, preinjury alcohol abuse, pre-injury psychiatric history, and severity of TBI. Symptom reporting is common following a traumatic injury and continues to be experienced by a substantial number of TBI subjects of all severity levels at 1 year post-injury.
这项研究调查了在颅脑外伤（TBI）后 1 个月和 1 年时，广泛损伤严重程度的患者与未头部受伤的患者相比，新出现或更严重的创伤后症状的报告率，并评估了与受伤后 1 年时症状报告相关的变量。732 名 TBI 受试者和 120 名普通创伤对照（TC）受试者在受伤后 1 个月和/或 1 年时提供了新的或更严重的症状信息。根据基本人口统计学、既往疾病和脑损伤严重程度，在亚组中比较了受伤后 1 年的症状报告。TBI 组在受伤后 1 个月和 1 年的报告的症状明显多于 TC（p<0.001）。尽管症状从 1 个月到 1 年有所缓解，但仍有 53%的 TBI 患者和 24%的 TC 患者在受伤后 1 年仍报告有 3 种或更多症状。TBI 组的症状报告与年龄、性别、受伤前酗酒、受伤前精神病史和 TBI 严重程度显著相关。创伤后症状报告很常见，在受伤后 1 年时，所有严重程度水平的 TBI 患者中仍有相当数量的患者持续经历症状。
