透明质酸结合和顶体酶活性在脊髓损伤男性的精子中降低。
Hyaluronic acid binding and acrosin activity are decreased in sperm from men with spinal cord injury.
机构信息
The Miami Project to Cure Paralysis, Department of Urology, University of Miami Miller School of Medicine, Miami, Florida, USA.
出版信息
Fertil Steril. 2010 Oct;94(5):1925-7. doi: 10.1016/j.fertnstert.2010.01.015. Epub 2010 Feb 26.
In this study, acrosin activity and hyaluronic acid binding were compared in sperm from men with spinal cord injury versus sperm from healthy controls. The results showed statistically significantly lower acrosin activity and statistically significantly lower hyaluronic acid binding in spinal cord injured patients compared with controls, indicating functional impairments that may diminish the capacity of the sperm to fertilize oocytes.
在这项研究中，比较了脊髓损伤男性患者和健康对照组精子的顶体酶活性和透明质酸结合能力。结果显示，与对照组相比，脊髓损伤患者的顶体酶活性显著降低，透明质酸结合能力显著降低，表明精子的功能受损，可能降低其受精卵子的能力。
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