左心室收缩功能障碍是否是勃起功能障碍的一个危险因素？

Is left ventricular systolic dysfunction a risk factor for erectile dysfunction?

机构信息

Department of Urology and Andrology, Danube Hospital, Vienna, Austria.

出版信息

Urology. 2010 May;75(5):1104-7. doi: 10.1016/j.urology.2009.11.040. Epub 2010 Feb 25.

DOI:10.1016/j.urology.2009.11.040

PMID:20188404

Abstract

OBJECTIVES

To analyze erectile dysfunction (ED) in patients with left ventricular systolic dysfunction (LVSD).

METHODS

A consecutive series of men aged 50-65 years undergoing an echocardiography (EC) at the Danube hospital in Vienna was analyzed. All patients completed the International Index of Erectile Function-5 (IIEF-5). LVSD was defined by EC as an ejection fraction (EF) below 55%.

RESULTS

A total of 85 men (age, 58.5 years; standard deviation, 4.3) entered the analysis. Mean EF was 60.9% and mean IIEF-5 score 16.8. No ED (IIEF-5, 22-25) was present in 32 men (37.6%), mild ED (IIEF-5, 17-21) in 17 (20%), and 36 (42.4%) had moderate to severe ED (IIEF-5, 5-16). An EF below 55% was seen in 26 men (30.6%). Mean IIEF-5 in men with LVSD was 13.6 compared with 18.2 in those without LVSD (P = .005); the proportion of men with ED (IIEF-5 <22) was 76% in men with LVSD compared with 56.6% in those without LVSD (relative risk, 1.37; P = .05). In a logistic regression analysis adjusted for body mass index and age a declined IIEF-5 score was independently associated with a low EF (<or=55%) (P = .02).

CONCLUSIONS

Our data, generated via standardized assessment of LVSD (EC) and ED (IIEF-5) revealed a significant effect of chronic LVSD on erectile function in middle-aged men.

摘要

目的

分析左心室收缩功能障碍（LVSD）患者的勃起功能障碍（ED）。

方法

对维也纳多瑙河医院进行超声心动图（EC）检查的连续 50-65 岁男性进行了分析。所有患者均完成了国际勃起功能指数-5（IIEF-5）的测试。LVSD 通过 EC 定义为射血分数（EF）低于 55%。

结果

共有 85 名男性（年龄 58.5 岁，标准差 4.3）进入分析。平均 EF 为 60.9%，平均 IIEF-5 评分为 16.8。32 名男性（37.6%）无 ED（IIEF-5，22-25），17 名男性（20%）轻度 ED（IIEF-5，17-21），36 名男性（42.4%）中至重度 ED（IIEF-5，5-16）。26 名男性（30.6%）EF 低于 55%。LVSD 男性的平均 IIEF-5 为 13.6，而无 LVSD 男性的平均 IIEF-5 为 18.2（P=.005）；LVSD 男性 ED（IIEF-5<22）的比例为 76%，而无 LVSD 男性的比例为 56.6%（相对风险，1.37；P=.05）。在调整了体重指数和年龄的 logistic 回归分析中，IIEF-5 评分下降与 EF 降低（<或=55%）独立相关（P=.02）。