Intermountain Medical Center and Intermountain Healthcare, Cardiac Transplant Program, Salt Lake City, Utah 84107, USA.
J Heart Lung Transplant. 2010 Apr;29(4):389-94. doi: 10.1016/j.healun.2009.10.016. Epub 2010 Feb 26.
Recent years have seen a rising awareness of the significance of cardiac antibody-mediated rejection (AMR) as a result of its formal recognition by the International Society for Heart and Lung Transplantation. New insights on the pathology and clinical behavior of cardiac AMR are at odds with current diagnostic guidelines. This perspective examines some of the contentious and unresolved issues in cardiac AMR as the transplant community makes concrete steps towards updating its defining criteria.
近年来，由于国际心肺移植学会正式承认，人们对心脏抗体介导排斥反应（AMR）的重要性的认识不断提高。对心脏 AMR 的病理学和临床行为的新认识与当前的诊断指南不一致。随着移植界朝着更新其定义标准迈出具体步骤，本观点探讨了心脏 AMR 中一些有争议和未解决的问题。
