Thariat J, de Mones E, Darcourt V, Poissonnet G, Marcy P-Y, Guevara N, Bozec A, Ortholan C, Santini J, Bensadoun R-J, Dassonville O
Service de radiothérapie, centre Antoine-Lacassagne, 33 avenue de Valombrose, Nice, France.
Cancer Radiother. 2010 Apr;14(2):137-44. doi: 10.1016/j.canrad.2009.09.010. Epub 2010 Feb 26.
Pre-irradiation dental care depends on teeth health, fields and dose of irradiation, compliance to fluorides, cessation of tobacco and psychosocial cofactors. Dental care aims at preventing complications and preserving the quality of life (eating, speech, and aesthetics). The role of hyperbaric oxygenotherapy for the prevention of osteoradionecrosis after teeth removal on the mandibula in areas receiving 50 Gy or more is still controversial. Medical treatments may be sufficient for early stages of osteoradionecrosis (antibiotics, pain killers, non-steroidal anti-inflammatory drugs as well as clodronate, vitamin E, pentoxifyllin). However, reconstructive surgery should not be delayed in advanced stages of osteoradionecrosis. New irradiation techniques are changing dose distributions and therefore require close collaboration between odonto-stomatologists and radiation oncologists to define the best dental care.
