Department of Radiation Oncology/Institut Universitaire de la Face et du Cou fo J thariat, Cancer Center Antoine-Lacassagne, University Nice Sophia-Antipolis, 33 Av. Valombrose, 06189, NICE Cedex 2, France.
Support Care Cancer. 2012 Aug;20(8):1811-4. doi: 10.1007/s00520-011-1279-5. Epub 2011 Sep 25.
The purpose of this study is to assess compliance with fluoride gel custom trays in irradiated head and neck cancer patients.
One hundred fifty-five consecutive patients on remission following radiation therapy of head and neck cancers were assessed retrospectively for dental care practices prior to radiation and prospectively for long-term compliance with custom trays from November 2009 to January 2010. A five-item questionnaire was filled in by patients in the waiting room, and a 15-item questionnaire by the physician in charge during the corresponding follow-up visit.
Ten percent of patients were edentulous at inclusion. Among dentate patients, 17% had total extractions. With a mean follow-up of 24 months, 19% of patients used custom trays for over a year. Primary stage, age, and tobacco consumption were correlated with compliance with custom trays. More than half of dentate patients developed carious lesions, and 8% had stage 1-3 osteoradionecrosis of the whole population of edentulous and dentate patients.
Compliance with custom trays was poor in this series. Specific postirradiation dental care follow-up visits and education have demonstrated their utility in the era of 2D irradiation. We currently advocate an 18-month compliance with custom trays in IMRT patients on the basis of the Parsport trial, after which we assess the quality of salivary recovery before recommending prolonged use or interruption. Data with innovative irradiation techniques are however required.
本研究旨在评估放疗后头颈部癌症患者使用氟凝胶定制托盘的依从性。
回顾性评估 155 例头颈部癌症放疗后缓解的连续患者在放疗前的口腔保健情况,并前瞻性评估 2009 年 11 月至 2010 年 1 月使用定制托盘的长期依从性。患者在候诊室填写五项目问卷,主管医生在相应的随访时填写十五项目问卷。
纳入时 10%的患者无牙,在有牙患者中,17%的患者进行了全口拔牙。平均随访 24 个月后,19%的患者使用定制托盘超过一年。原发阶段、年龄和吸烟与使用定制托盘的依从性相关。超过一半的有牙患者出现龋齿,8%的无牙和有牙患者发生了整个群体的 1-3 级放射性骨坏死。
本系列中,定制托盘的依从性较差。特定的放疗后口腔保健随访和教育已经证明了它们在二维放疗时代的实用性。我们目前根据 Parsport 试验主张在调强放疗患者中使用定制托盘 18 个月,然后评估唾液恢复质量,再决定是否推荐延长使用或中断使用。然而,需要创新性的放疗技术数据。