Department of Chemical Engineering, Massachusetts Institute of Technology, 770 Massachusetts Avenue, Cambridge, MA 02139, USA.
Immunity. 2010 Feb 26;32(2):141-2. doi: 10.1016/j.immuni.2010.02.005.
Does the affinity or half-life of peptide-MHC-T cell receptor (TCR) interactions determine T cell activation? In this issue of Immunity, Aleksic et al. (2010) propose a role for the on rate through multiple rebindings to the same TCR.
肽-MHC-T 细胞受体（TCR）相互作用的亲和力或半衰期是否决定 T 细胞的激活？在本期《免疫》中，Aleksic 等人（2010 年）提出了通过与同一 TCR 多次重新结合来提高结合速率的作用。
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