免疫突触中的信号传导：确定最佳大小。
Signaling in the immunological synapse: defining the optimal size.
作者信息
Kupfer Abraham
机构信息
Department of Cell Biology and Program in Immunology at Institute for Cell Engineering, Johns Hopkins University School of Medicine, 733 N. Broadway, BRB Room 623, Baltimore, Maryland 21205, USA.
出版信息
Immunity. 2006 Jul;25(1):11-3. doi: 10.1016/j.immuni.2006.07.005.
PMID:16860751
Abstract
In this issue of Immunity, Varma et al. (2006) report that in the synapses between T cells and planar bilayers, T cell receptor (TCR) proximal signaling takes place in peripheral TCR-microclusters that form continually and that TCR signaling ceases when they fuse with the central supramolecular activation cluster.
摘要
在本期《免疫》杂志中，瓦尔马等人（2006年）报告称，在T细胞与平面双层膜之间的突触中，T细胞受体（TCR）近端信号传导发生在不断形成的外周TCR微簇中，并且当这些微簇与中央超分子激活簇融合时，TCR信号传导就会停止。
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