树突状细胞亚群被消化：RNA 感应带来的不同！

Dendritic cell subsets digested: RNA sensing makes the difference!

机构信息

Department of Tumor Immunology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, 6500 HB, Nijmegen, the Netherlands.

出版信息

Immunity. 2010 Feb 26;32(2):149-51. doi: 10.1016/j.immuni.2010.02.006.

DOI:10.1016/j.immuni.2010.02.006

PMID:20189479

Abstract

In this issue of Immunity, Luber et al. (2010) report a comprehensive quantitative proteome of in vivo mouse spleen dendritic cell (DC) subsets: a data set of encyclopedic value already revealing that DC subsets exploit different RNA sensors for virus recognition.

摘要

本期《免疫》杂志上，Luber 等人（2010 年）报道了体内小鼠脾脏树突状细胞（DC）亚群的全面定量蛋白质组学：这一具有百科全书价值的数据集已经揭示，DC 亚群利用不同的 RNA 传感器来识别病毒。