Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.
Gastrointest Endosc. 2010 Mar;71(3):573-7. doi: 10.1016/j.gie.2009.10.042.
Polyethylene glycol (PEG) 3350 is commonly used and has been proven safe and effective for the treatment of chronic constipation and as a 4-day bowel preparation in children. A 1-day PEG 3350 bowel preparation regimen has been recently developed for adults; however, data regarding its use in children are lacking.
To evaluate the safety and effectiveness of a 1-day PEG 3350 regimen for bowel preparation in children before colonoscopy.
Retrospective review.
Tertiary-care center.
This study involved all children prescribed a 1-day PEG 3350 bowel preparation regimen before colonoscopy at our center in 2008.
We reviewed medical records of patients (< or = 18 years of age) who underwent colonoscopy during 2008 and received the 1-day bowel preparation regimen.
Adequate preparation for colonoscopy, success of colonoscopy, and factors associated with inadequate bowel preparation.
Inclusion criteria were met by 272 patients. The median age of the children receiving the 1-day PEG 3350 preparation regimen was 13.7 years (range 1.08-17.92 years). Fifty-two percent were male; 48% were female. The most common indications for colonoscopy included abdominal pain (65%), bloody stools (29%), diarrhea (21%), and weight loss (18%). The 1-day bowel preparation regimen was effective in 253 patients (93%). The indication for colonoscopy, the age of the child, or a history of constipation did not significantly alter the success rate of colonoscopy.
A retrospective study at one tertiary-care center.
The 1-day PEG 3350 bowel preparation regimen is safe and effective and should be considered for use as preparation for colonoscopy in children.
聚乙二醇 3350 常用于治疗慢性便秘，且已被证实安全有效，也可作为儿童 4 天肠道准备的药物。近期研发了一种用于成人的 1 天 PEG 3350 肠道准备方案，但在儿童中的应用数据尚缺乏。
评估 1 天 PEG 3350 肠道准备方案在儿童结肠镜检查前的安全性和有效性。
回顾性研究。
三级医疗中心。
本研究纳入了 2008 年在本中心行结肠镜检查且接受 1 天 PEG 3350 肠道准备方案的所有儿童患者。
我们回顾了 2008 年接受结肠镜检查且接受 1 天肠道准备方案的患者（年龄≤18 岁）的病历。
结肠镜检查的肠道准备充分情况、结肠镜检查的成功率以及与肠道准备不充分相关的因素。
272 例患者符合纳入标准。接受 1 天 PEG 3350 准备方案的儿童的中位年龄为 13.7 岁（范围 1.08~17.92 岁）。52%为男性；48%为女性。结肠镜检查的主要适应证包括腹痛（65%）、血便（29%）、腹泻（21%）和体重减轻（18%）。253 例（93%）患者的 1 天肠道准备方案有效。结肠镜检查适应证、儿童年龄或便秘史并未显著改变结肠镜检查的成功率。
在一家三级医疗中心进行的回顾性研究。
1 天 PEG 3350 肠道准备方案安全有效，可考虑用于儿童结肠镜检查前的肠道准备。
