Research Department of Infection and Population Health, University College London, Hampstead Campus, London, United Kingdom.
Am J Infect Control. 2010 May;38(4):332-4. doi: 10.1016/j.ajic.2009.10.005. Epub 2010 Mar 1.
Trials evaluating interventions to improve health care workers' hand hygiene compliance use directly observed compliance as a primary outcome measure. Observers should be blinded to the intervention and the effectiveness of blinding assessed to prevent systematic bias. The literature has not addressed this issue, and this study describes a robust and pragmatic method for assessing the adequacy of blinding in hand hygiene intervention trials.
评估干预措施以提高医护人员手部卫生依从性的试验使用直接观察的依从性作为主要结果测量指标。观察者应对干预措施和盲法效果保持盲态,以防止系统偏差。文献尚未解决这一问题,本研究描述了一种用于评估手部卫生干预试验中盲法充分性的强大而实用的方法。