Iowa Comprehensive Epilepsy Program, Center for Sleep Medicine, Division of Pulmonary and Critical Care, Department of Medicine and Neurology, Medical Clinic and Foundation, Rochester, Minnesota 55095, USA.
Epileptic Disord. 2010 Mar;12(1):76-80. doi: 10.1684/epd.2010.0294. Epub 2010 Mar 1.
A 23-year-old woman without history of antecedent vocal, respiratory, or sleep disorders received vagus nerve stimulation (VNS) therapy for refractory partial epilepsy and developed sleep-related stridor during the course of parameter titration. Reduction of VNS current during polysomnography completely eliminated stridor. We conclude that VNS may cause sleep-related stridor in rare cases, expanding the spectrum of known sleep-disordered breathing disorders associated with VNS therapy. Parameter adjustment during polysomnography may resolve nocturnal stridor caused by VNS.
一位 23 岁的女性,既往无嗓音、呼吸或睡眠障碍史,因耐药性部分性癫痫接受迷走神经刺激(VNS)治疗,并在参数滴定过程中出现与睡眠相关的喘鸣。在睡眠多导图检查时降低 VNS 电流可完全消除喘鸣。我们得出结论,VNS 可能在极少数情况下引起与睡眠相关的喘鸣,扩大了与 VNS 治疗相关的已知睡眠呼吸障碍疾病谱。在睡眠多导图检查期间进行参数调整可能解决 VNS 引起的夜间喘鸣。