National Marrow Donor Program, Minneapolis, MN 55413, USA.
Bone Marrow Transplant. 2010 May;45(5):825-31. doi: 10.1038/bmt.2010.11. Epub 2010 Mar 1.
The international exchange of cord blood units (CBUs) for transplantation has brought new challenges to the stem cell donor registries involved in the exchange of BM and PBSCs. The unique properties of cord blood cells and differences in the search processes between CBUs and adult unrelated donors has required registries responsible for cord blood bank (CBB) networks to review their current practices and to develop new processes to accommodate for the provision of CBUs. This paper describes the aims and activities of the World Marrow Donor Association (WMDA) Cord Blood Working Group (CBWG) which was established in 2007 to gather and exchange information about cord blood registry needs and activities, and to develop guidelines to support and promote safe effective international exchange of unrelated CBUs for transplantation.
国际间脐带血单位(CBUs)的交流为参与骨髓和外周血干细胞(PBSCs)交流的干细胞供者登记处带来了新的挑战。脐带血细胞的独特性质以及 CBU 与成人非亲缘供者之间的搜索过程的差异,要求负责脐带血库(CBB)网络的登记处审查其当前做法,并制定新的流程,以提供 CBUs。本文介绍了世界骨髓捐献者协会(WMDA)脐带血工作组(CBWG)的目标和活动,该工作组成立于 2007 年,旨在收集和交流有关脐带血登记处需求和活动的信息,并制定指南,以支持和促进非亲缘关系的 CBU 安全有效地进行国际间移植交流。