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Selective digestive tract decontamination: A tough pill to swallow.选择性消化道去污：难以下咽的苦药。
Can J Infect Dis Med Microbiol. 2009 Spring;20(1):9-11. doi: 10.1155/2009/290130.
2
Selective decontamination of the digestive tract.消化道选择性去污
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Selective decontamination of the digestive tract in critically ill children: systematic review and meta-analysis.危重症患儿消化道去污染：系统评价和荟萃分析。
Pediatr Crit Care Med. 2013 Jan;14(1):89-97. doi: 10.1097/PCC.0b013e3182417871.
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Selective decontamination of the digestive tract prevents secondary infection of the abdominal cavity, and endotoxemia and mortality in sterile peritonitis in laboratory rats.消化道选择性去污可预防实验大鼠无菌性腹膜炎时腹腔的继发性感染、内毒素血症及死亡。
Crit Care Med. 1992 Dec;20(12):1699-704. doi: 10.1097/00003246-199212000-00017.
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Impact of selective decontamination of the digestive tract on multiple organ dysfunction syndrome: systematic review of randomized controlled trials.消化道选择性去污染对多器官功能障碍综合征的影响：随机对照试验的系统评价。
Crit Care Med. 2010 May;38(5):1370-6. doi: 10.1097/CCM.0b013e3181d9db8c.
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Selective decontamination of the digestive tract in surgical patients: a systematic review of the evidence.外科患者消化道的选择性去污：证据的系统评价
Arch Surg. 1999 Feb;134(2):170-6. doi: 10.1001/archsurg.134.2.170.
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Selective decontamination of the digestive tract in cardiac surgical patients.心脏外科手术患者消化道的选择性去污
Crit Care Med. 1991 Dec;19(12):1486-90. doi: 10.1097/00003246-199112000-00008.
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Selective decontamination of the digestive tract in neurosurgical intensive care unit patients: a double-blind, randomized, placebo-controlled study.神经外科重症监护病房患者的消化道选择性去污：一项双盲、随机、安慰剂对照研究。
Crit Care Med. 1993 Oct;21(10):1466-73. doi: 10.1097/00003246-199310000-00013.
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Meta-analysis of randomised controlled trials of selective decontamination of the digestive tract. Selective Decontamination of the Digestive Tract Trialists' Collaborative Group.消化道选择性去污随机对照试验的荟萃分析。消化道选择性去污试验协作组
BMJ. 1993 Aug 28;307(6903):525-32. doi: 10.1136/bmj.307.6903.525.
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Long-term effects of selective decontamination on antimicrobial resistance.选择性去污对抗菌药物耐药性的长期影响。
Crit Care Med. 1995 Apr;23(4):637-45. doi: 10.1097/00003246-199504000-00010.

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Causal Relationship Between Gut Microbiota and Leukemia: Future Perspectives.肠道微生物群与白血病之间的因果关系：未来展望
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Selective Intestinal Decontamination as a Method for Preventing Infectious Complications (Review).选择性肠道去污染作为预防感染性并发症的一种方法（综述）。
Sovrem Tekhnologii Med. 2021;12(6):86-95. doi: 10.17691/stm2020.12.6.10. Epub 2020 Dec 28.
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Selective decontamination of the digestive tract: the mechanism of action is control of gut overgrowth.选择性消化道去污：作用机制是控制肠道过度生长。
Intensive Care Med. 2012 Nov;38(11):1738-50. doi: 10.1007/s00134-012-2690-1. Epub 2012 Sep 22.
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Long-term use of selective decontamination of the digestive tract does not increase antibiotic resistance: a 5-year prospective cohort study.长期使用选择性消化道去污染不会增加抗生素耐药性：一项为期 5 年的前瞻性队列研究。
Intensive Care Med. 2011 Sep;37(9):1458-65. doi: 10.1007/s00134-011-2307-0. Epub 2011 Jul 19.
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Gut overgrowth harms the critically ill.肠道细菌过度生长对重症患者有害。
Intensive Care Med. 2011 Sep;37(9):1560; author reply 1561-2. doi: 10.1007/s00134-011-2287-0. Epub 2011 Jun 28.
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Current status on VAP prevention: evidence-based medicine makes the ethics of withholding SDD questionable.VAP预防的现状：循证医学使不采用SDD的伦理问题受到质疑。
J Clin Monit Comput. 2010 Aug;24(4):305-6. doi: 10.1007/s10877-010-9249-x. Epub 2010 Jul 23.

本文引用的文献

1
Decontamination of the digestive tract and oropharynx in ICU patients.重症监护病房患者消化道和口咽的去污处理
N Engl J Med. 2009 Jan 1;360(1):20-31. doi: 10.1056/NEJMoa0800394.
2
Surviving Sepsis Campaign needed consensus to exclude selective decontamination of the digestive tract.拯救脓毒症运动需要达成共识以排除消化道选择性去污。
Crit Care Med. 2008 Sep;36(9):2716-7. doi: 10.1097/CCM.0b013e31818474a2.
3
SMART approaches for reducing nosocomial infections in the ICU.重症监护病房减少医院感染的明智方法。
Chest. 2008 Aug;134(2):447-456. doi: 10.1378/chest.08-0809.
4
Comprehensive evidence-based clinical practice guidelines for ventilator-associated pneumonia: prevention.呼吸机相关性肺炎的综合循证临床实践指南：预防
J Crit Care. 2008 Mar;23(1):126-37. doi: 10.1016/j.jcrc.2007.11.014.
5
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.拯救脓毒症运动：严重脓毒症和脓毒性休克治疗国际指南：2008年版
Crit Care Med. 2008 Jan;36(1):296-327. doi: 10.1097/01.CCM.0000298158.12101.41.
6
Adequacy of empirical antifungal therapy and effect on outcome among patients with invasive Candida species infections.经验性抗真菌治疗的充分性及其对侵袭性念珠菌属感染患者预后的影响。
J Antimicrob Chemother. 2007 Sep;60(3):613-8. doi: 10.1093/jac/dkm212. Epub 2007 Jun 18.
7
The effect of selective decontamination of the digestive tract on mortality in multiple trauma patients: a multicenter randomized controlled trial.消化道选择性去污对多发伤患者死亡率的影响：一项多中心随机对照试验
Intensive Care Med. 2007 Feb;33(2):261-70. doi: 10.1007/s00134-006-0455-4. Epub 2006 Dec 5.
8
Selective digestive tract decontamination--will it prevent infection with multidrug-resistant gram-negative pathogens but still be applicable in institutions where methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci are endemic?选择性消化道去污——它能否预防耐多药革兰氏阴性病原体感染，但仍适用于耐甲氧西林金黄色葡萄球菌和耐万古霉素肠球菌流行的机构？
Clin Infect Dis. 2006 Sep 1;43 Suppl 2:S70-4. doi: 10.1086/504482.
9
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.在开始有效的抗菌治疗之前低血压的持续时间是人类感染性休克生存的关键决定因素。
Crit Care Med. 2006 Jun;34(6):1589-96. doi: 10.1097/01.CCM.0000217961.75225.E9.
10
Survival benefit in critically ill burned patients receiving selective decontamination of the digestive tract: a randomized, placebo-controlled, double-blind trial.接受消化道选择性去污的重症烧伤患者的生存获益：一项随机、安慰剂对照、双盲试验。
Ann Surg. 2005 Mar;241(3):424-30. doi: 10.1097/01.sla.0000154148.58154.d5.

Selective digestive tract decontamination: A tough pill to swallow.

作者信息

Laupland Kevin B, Fisman David N

机构信息

Departments of Medicine, Critical Care Medicine, Pathology and Laboratory Medicine, Centre for Antimicrobial Resistance, University of Calgary, Calgary Laboratory Services, Calgary Health Region, Calgary, Alberta;

出版信息

Can J Infect Dis Med Microbiol. 2009 Spring;20(1):9-11. doi: 10.1155/2009/290130.

DOI:10.1155/2009/290130
PMID:20190888
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2690518/
Abstract
摘要