Tang Xiao-yan, Xu Bian-li, Guo Wan-shen, Li Xing-le
Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450016, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2009 Sep;30(9):923-6.
To analyze the characteristics and trend of Japanese encephalitis (JE) in Henan province.
Adopting descriptive epidemiological method to analyze the data on the epidemic situation of JE from 1950 to 2008, and on mosquitoes and host animals at disease surveillance points. The host serum JE IgG antibody was detected by ELISA. Data was analyzed using SPSS 12.0 and Excel 2003 software.
The incidence of JE in Henan province had a fluctuant downward trend. Peak of the incidence fell in July to September, accounting for 88.09% of total cases. The scope of geographical distribution was increasing from northern to southern parts of the province. Cases mainly concentrated in the southern and south-eastern parts of the province. 0 - 14 year-old group had the highest incidence (81.95%). In Luoyang city, there was a significant increase in children at 15-years or older (58.93%). Most patients were farmers (42.33%). The positive-times for half of the antibodies of JE in piglets of the surveillance sentinels were different, which might be the reason for the different levels for the incidence rates. The proportion of different kinds of mosquitoes were also different in surveillance sentinel sites, and the time for the density peak of the mosquitoes was in accordance with the incidence peak of JE.
To develop control strategies, evidence should be based on the characteristics of geographical variance, age, occupation differences, data related to monitoring on animal host and media mosquitoes of JE incidence in Henan province.
分析河南省流行性乙型脑炎（乙脑）的流行特征及变化趋势。
采用描述性流行病学方法，对1950 - 2008年乙脑疫情资料以及疾病监测点蚊虫和宿主动物资料进行分析。采用酶联免疫吸附试验（ELISA）检测宿主血清乙脑IgG抗体。运用SPSS 12.0和Excel 2003软件进行数据分析。
河南省乙脑发病率呈波动下降趋势。发病高峰集中在7 - 9月，占总病例数的88.09%。地理分布范围由北向南扩大，病例主要集中在豫南和豫东南地区。0 - 14岁组发病率最高（81.95%），洛阳市15岁及以上儿童发病率显著上升（58.93%）。患者以农民为主（42.33%）。监测哨点仔猪乙脑抗体半数阳性次数不同，可能是发病率水平差异的原因。监测哨点不同种类蚊虫比例不同，蚊虫密度高峰时间与乙脑发病高峰一致。
制定防控策略应依据河南省乙脑发病的地理差异、年龄、职业差异以及动物宿主和媒介蚊虫监测资料特点。
