Yang Wan-shui, Yang Chi, Zheng Jia-wei, Gao Jing, Zhang Wei, Zhang Zhi-yuan, Xiang Yong-bing
School of Public Health, Fudan University, Shanghai 200032, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2009 Nov;30(11):1171-4.
To explore the secular trend of incidence for nasopharyngeal carcinoma (NPC) in urban Shanghai during 1973 - 2005.
The incidence data from the population-based cancer registries in Shanghai was used in our analysis. We calculated the crude incidence rates, age-adjusted incidence rates, truncated rates and cumulative rates of NPC. The annual percentage change (APC) was used as an estimate of the secular trend.
Over 33 years, a total of 7889 incident NPC cases in urban Shanghai were registered for 5555 males and 2334 females, respectively. The incidence of NPC had remained stable in males during the period (APC = -0.250%, P = 0.340), but a decreasing trend was observed in females with an average reduction of -1.577% (P = 0.000) per year. During the period of 1973 - 1976 to 2001 - 2005, the crude incidence rates changed from 4.56 to 6.18 and from 3.96 to 2.41 per 100 000 in males and females, and the age-adjusted rates from 4.12 to 3.96 and from 2.18 to 3.42 per 100 000 in males and females, respectively.
From 1973 to 2005, the incidence of NPC was stable in males while having a decline in females, indicating that further epidemiological study and prevention for NPC should be addressed.
探讨1973 - 2005年上海市市区鼻咽癌（NPC）发病率的长期变化趋势。
分析上海市基于人群的癌症登记处的发病率数据。我们计算了NPC的粗发病率、年龄调整发病率、截缩发病率和累积发病率。采用年度百分比变化（APC）来估计长期变化趋势。
在33年期间，上海市市区共登记了7889例NPC新发病例，其中男性5555例，女性2334例。在此期间，男性NPC发病率保持稳定（APC = -0.250%，P = 0.340），但女性发病率呈下降趋势，平均每年下降-1.577%（P = 0.000）。在1973 - 1976年至2001 - 2005年期间，男性和女性的粗发病率分别从每10万4.56例和3.96例变为6.18例和2.41例，年龄调整发病率分别从每10万4.12例和2.18例变为3.96例和3.42例。
1973年至2005年，男性NPC发病率稳定，而女性发病率下降，表明应进一步开展NPC的流行病学研究和预防工作。
