Wei Kuang-Rong, Zheng Rong-Shou, Zhang Si-Wei, Liang Zhi-Heng, Li Zhu-Ming, Chen Wan-Qing
Cancer Institute of Zhongshan People's Hospital, Zhongshan, Guangdong, 528403, P. R. China.
National Central Cancer Registry, National Cancer Center, Beijing, 100021, P. R. China.
Chin J Cancer. 2017 Nov 9;36(1):90. doi: 10.1186/s40880-017-0257-9.
We estimated the incidence and mortality of nasopharyngeal carcinoma (NPC) in China in 2010 according to the data of 145 domestic population-based cancer registries in 2014, and no such reports since then. Hence, to further and better understand its epidemiology in China and to provide more precise scientific information for its control and prevention in China, we analyzed the NPC incidence and mortality of 255 domestic population-based cancer registries, and estimated the national rates in 2013 again.
NPC incidence and mortality data of 255 domestic cancer registries in 2013, accepted by the 2016 National Cancer Registry Annual Report, were collected and collated, and the indices of NPC such as the numbers of new cases and deaths, crude rates, age-standardized rates, and truncated rates of incidence and mortality were calculated and analyzed. The incidence and mortality in China and its constituent areas were estimated according to the national population in 2013.
An estimated 42,100 new cases and 21,320 deaths were attributed to NPC in China in 2013, accounting for 1.14% of all new cancer cases and 0.96% of all cancer-related deaths that year in China. Crude incidence and mortality of NPC were 3.09/100,000 and 1.57/100,000, respectively. World age-standardized incidence and mortality were 2.17/100,000 and 1.08/100,000, respectively. The incidence and mortality of males were obviously higher than those of females and slightly higher in urban areas than in rural areas. Among seven Chinese administrative regions, NPC incidence and mortality were obviously higher in South China than in other regions and lowest in North China. Top 3 incidence and mortality provinces and registering areas all located in South China. The age-specific incidence and mortality rose quickly from age 25-29 and 35 to 39 years, respectively, peaked at different ages and varied by location.
These results demonstrated that NPC incidence and mortality in China in 2013 were also at high levels worldwide, which suggested that its control and prevention should be enhanced.
我们根据2014年国内145个基于人群的癌症登记处的数据，估算了2010年中国鼻咽癌（NPC）的发病率和死亡率，此后未见此类报告。因此，为了进一步更好地了解其在中国的流行病学情况，并为中国的控制和预防提供更精确的科学信息，我们分析了255个国内基于人群的癌症登记处的鼻咽癌发病率和死亡率，并再次估算了2013年的全国发病率和死亡率。
收集并整理了2016年《中国肿瘤登记年报》收录的2013年255个国内癌症登记处的鼻咽癌发病率和死亡率数据，并计算和分析了鼻咽癌的新发病例数、死亡数、粗发病率、年龄标准化发病率以及发病和死亡的截缩率等指标。根据2013年全国人口估算了中国及其各地区的发病率和死亡率。
2013年中国估计有42100例鼻咽癌新发病例和21320例死亡病例，分别占当年中国所有新发癌症病例的1.14%和所有癌症相关死亡病例的0.96%。鼻咽癌的粗发病率和死亡率分别为3.09/10万和1.57/10万。世界年龄标准化发病率和死亡率分别为2.17/10万和1.08/10万。男性的发病率和死亡率明显高于女性，城市地区略高于农村地区。在中国七个行政区中，华南地区的鼻咽癌发病率和死亡率明显高于其他地区，华北地区最低。发病率和死亡率排名前3的省份和登记地区均位于华南地区。特定年龄的发病率和死亡率分别在25 - 29岁和35至39岁时迅速上升，在不同年龄达到峰值，并因地区而异。
这些结果表明，2013年中国鼻咽癌的发病率和死亡率在全球范围内也处于较高水平，这表明应加强其控制和预防。
