Institute of Forensic Medicine, University of Bonn, Germany.
Forensic Sci Int. 2010 May 20;198(1-3):e1-4. doi: 10.1016/j.forsciint.2010.01.007. Epub 2010 Mar 2.
Diagnosis of lethal anaphylaxis is known to be difficult to establish in forensic autopsy. Cases of anaphylactic shock have to be dealt with in forensic medicine comparatively frequently as death due to anaphylaxis is likely to occur rapidly and without warning in seemingly healthy subjects. Autopsy findings might hint at allergic reaction, but classic manifestations can also be completely absent. A case of suspected food anaphylaxis in a middle-aged woman is presented. The deceased had been known to suffer from multiple allergies. Death came about after an evening meal with friends. Dyspnoea was reported to have been followed by collapse, unconsciousness and death within minutes. The course of further analysis undertaken (toxicology, biochemistry, immunohistochemistry) is examplarily described. By means of the results presented we discuss problems and possibilities of postmortem diagnostics of food induced anaphylaxis.
在法医解剖中，已知致命性过敏反应的诊断具有一定难度。在法医学中，过敏反应性休克的案例较为常见，因为过敏反应可能导致看似健康的个体迅速且毫无预警地死亡。尸检结果可能提示过敏反应，但经典表现也可能完全缺失。本文呈现了一起中年女性疑似食物过敏反应的案例。该死者已知患有多种过敏症。其在与朋友共进晚餐后死亡。据报道，死者先出现呼吸困难，随后在数分钟内发生晕倒、意识丧失和死亡。本文还对进一步进行的分析（毒理学、生物化学、免疫组织化学）进行了举例描述。通过呈现的结果，我们讨论了食物诱导过敏反应的死后诊断的问题和可能性。
