空泡性耳硬化症：临床、放射学和组织病理学相关性。
Cavitating otosclerosis: clinical, radiologic, and histopathologic correlations.
机构信息
Department of Histopathology, House Ear Institute, UCLA Medical Center, Los Angeles, California, U.S.A.
出版信息
Otol Neurotol. 2010 Apr;31(3):381-4. doi: 10.1097/MAO.0b013e3181d275e8.
BACKGROUND
Despite the high prevalence of otosclerosis and its having long been a subject of scrutiny, cavitary changes in otosclerosis are rare and not well known. Here, we describe and introduce into the literature the unusual histologic and radiologic findings of cavitation and its possible clinical relevance in patients with advanced cochlear otosclerosis.
METHODS
Cases with clinical otosclerosis and presence of cavitation were selected from our temporal bone collection and correlated with premortem imaging and clinical manifestations.
RESULTS
Two cases of cochlear otosclerosis presented with a clinical syndrome possibly attributed to the existence of a cavity within the otosclerotic foci.
CONCLUSION
Cavitating otosclerosis is a not well-known occurrence in patients with advanced cochlear otosclerosis, and it is a possible cause of a "third window" syndrome and surgical complications.
背景
尽管耳硬化症的患病率很高，并且长期以来一直受到关注，但耳硬化症的空洞性改变却很少见，也不为人所知。在这里，我们描述并介绍了在晚期耳蜗耳硬化症患者中，空洞的异常组织学和影像学发现及其可能的临床相关性。
方法
从我们的颞骨标本库中选择有临床耳硬化症和空洞存在的病例，并与生前影像学和临床表现进行相关性分析。
结果
两例耳蜗耳硬化症患者出现了一种可能归因于耳硬化灶内存在空洞的临床综合征。
结论
空洞性耳硬化症在晚期耳蜗耳硬化症患者中是一种不太为人知的情况，它可能是“第三窗口”综合征和手术并发症的原因之一。
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