Department of Chemistry, Stanford University, Stanford, California 94305-5080, USA.
Org Lett. 2010 Apr 2;12(7):1604-7. doi: 10.1021/ol100337m.
A cationic rhodium(I) complex--(C(10)H(8))Rh(cod) SbF(6)(-)--catalyzes the remarkably efficient intermolecular [5 + 2] cycloaddition of vinylcyclopropanes (VCPs) and various alkynes, providing cycloheptene cycloadducts in excellent yields in minutes at room temperature. The efficacy and selectivity of this catalyst are also shown in a novel diversification strategy, affording a cycloadduct library in one step from nine commercially available components.
一种阳离子铑（I）配合物--[(C(10)H(8))Rh(cod)]SbF(6)(-)--能够高效地催化乙烯基环丙烷（VCPs）与各种炔烃的[5 + 2]环加成反应，在室温下仅需几分钟即可得到高产率的环庚烯环加成产物。该催化剂还具有很好的效果和选择性，在一种新颖的多样化策略中，仅从九个市售原料一步即可得到一个环加成产物库。
