Department of Chemistry, Center for Chemical Methodology and Library Development (CMLD-BU), Boston University , 590 Commonwealth Avenue, Boston, Massachusetts 02215, United States.
Org Lett. 2014 Jan 3;16(1):74-7. doi: 10.1021/ol403035g. Epub 2013 Dec 16.
A rhodium(II) catalyzed nitrene-alkyne cycloaddition of stereochemically well-defined homopropargylic ethers is followed by arene cyclopropanation to afford unique tetracyclic norcaradiene products bearing a cyclic sulfamate. Products from the arene cyclopropanation (Buchner reaction) can be converted to fused cycloheptatrienes via a ring enlarging electrocyclization after nucleophilic ring opening of the cyclic sulfamate ester.
铑（II）催化的立体定义良好的偕丙基醚的氮烯-炔环加成反应，接着进行芳环环丙烷化反应，得到独特的含有环状磺酰胺的四环降蒈烯产物。芳环环丙烷化（布赫纳反应）产物可以通过环状磺酰胺酯的亲核开环后进行扩环电环化，转化为稠合的环庚三烯。
