Isch-Treussard C, Bapst-Reiter J, Trapp C, Kurtz D
Rev Electroencephalogr Neurophysiol Clin. 1977 Apr-Jun;7(2):174-9. doi: 10.1016/s0370-4475(77)80076-2.
The authors report 3 cases of herpes encephalitis in children aged respectively 15 days, 12 months and 18 months. In all 3 cases E.E.G. activity of a periodic nature was noted, which was continuous or intermittent, lateralised or focal in the temporal region, appearing from the 4th to 7th day. The periodicity (of the E.E.G. complex) was short and their stereotyped appearance particularly unusual in babies. In all 3 children convulsive seizures occurred before the discovery of the periodic activity. The latter was found to change in morphology and timing during the seizures. The disease process led to death of the neonate, and recovery with serious sequellae in the other two children. Possible relationships between the transitory nature of the periodic acitivity, the age and the eventual course of the disease, were discussed.
作者报告了3例分别为15天、12个月和18个月大儿童的疱疹性脑炎病例。在所有3例病例中,均发现有周期性的脑电图活动,这种活动持续或间歇性出现,位于颞区,呈单侧或局灶性,于第4至7天出现。(脑电图复合波的)周期性较短,其刻板的表现形式在婴儿中尤为罕见。在所有3名儿童中,惊厥发作均先于周期性活动被发现。后者在惊厥发作期间形态和时间均发生变化。疾病过程导致新生儿死亡,另外两名儿童康复但伴有严重后遗症。文中讨论了周期性活动的短暂性、年龄与疾病最终病程之间可能存在的关系。