Cátedra de Neurología, Departamento de Medicina, Universidad de Valparaíso, Valparaíso, Chile.
Neuroepidemiology. 2010;34(4):214-21. doi: 10.1159/000289353. Epub 2010 Mar 3.
The incidence of intracerebral haemorrhage (ICH) in Hispanics is high, especially of non-lobar ICH. Our aim was to ascertain prospectively the incidence of first-ever spontaneous ICH (SICH) stratified by localisation in a Hispanic-Mestizo population of the north of Chile.
Between July 2000 and June 2002 all possible cases of ICH were ascertained from multiple overlapping sources. The cases were allocated according to localisation. Those with vascular malformations or non-identifiable localisations were excluded.
We identified a total of 69 cases of first-ever ICH. Of these, 64 (92.7%) had SICH, of which we allocated 58 cases (84%) to non-lobar or lobar localisation. The mean age was 57.3 +/- 17 years, and 62.3% of the subjects were male. The age-adjusted incidence rates were 13.8 (non-lobar) and 4.9 (lobar) per 100,000 person-years. Non-lobar SICH was more frequent in young males and lobar SICH in older women. The non-lobar-to-lobar ratio was similar to previous findings in Hispanics. Hypertension was more frequent in non-lobar SICH and in diabetes, heavy drinking and antithrombotic use in lobar SICH, but in none significantly. There was no association between localisation and prognosis.
The incidence of non-lobar SICH was high, but lower than in most non-white populations. This lower incidence could be due to a lower population prevalence of risk factors, a higher socioeconomic level in this population, or chance.
西班牙裔人群的脑出血（ICH）发病率较高，尤其是非脑叶 ICH。我们的目的是在智利北部的西班牙裔混血人群中，前瞻性地确定首次自发性脑出血（SICH）的发病情况，并按部位进行分层。
在 2000 年 7 月至 2002 年 6 月期间，通过多个重叠来源确定了所有可能的 ICH 病例。根据部位对病例进行分配。排除了有血管畸形或无法确定部位的病例。
我们共发现 69 例首次 ICH。其中 64 例（92.7%）为 SICH，其中 58 例（84%）为非脑叶或脑叶部位。平均年龄为 57.3 +/- 17 岁，62.3%的患者为男性。年龄调整后的发病率分别为每 100,000 人年 13.8 例（非脑叶）和 4.9 例（脑叶）。非脑叶 SICH 多见于年轻男性，而脑叶 SICH 多见于老年女性。非脑叶与脑叶的比值与之前西班牙裔人群的发现相似。非脑叶 SICH 中高血压更为常见，而脑叶 SICH 中糖尿病、大量饮酒和抗血栓药物使用更为常见，但均无显著差异。部位与预后之间无相关性。
非脑叶 SICH 的发病率较高，但低于大多数非白人群。这种较低的发病率可能是由于该人群的危险因素患病率较低、该人群的社会经济水平较高，或是偶然因素所致。
