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白癜风手术:在稳定期白癜风中作为一种明确治疗方法的演变。

Vitiligo surgery: its evolution as a definite treatment in the stable vitiligo.

机构信息

Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

G Ital Dermatol Venereol. 2010 Feb;145(1):79-88.

PMID:20197747
Abstract

Vitiligo is a common pigmentary disorder which causes immense psychosocial impact on the patients. This condition is still an enigma in terms of its pathogenesis and management. Although there are various treatment modalities, till date none of it takes care of the cause. Surgical management has evolved significantly and given a ray of hope in stable vitiligo. The main purpose is to review the various surgical modalities available along with a look on the milestones and an effort to find answers to "why, when, whom and how" of vitiligo surgery. This article is based on the review of medical literature regarding various surgical management of vitiligo and also author's experience in this particular field. In addition with this review authors tried to shed light on the factors affecting the outcome of vitiligo surgery. The outcome any surgical procedure in vitiligo depends on the proper patient selection, a proper knowledge of this condition and also about its mystery, an expertise in the procedure and a dedication towards patient care. It is certain that surgical modality will be chosen by many with the hope that it succeeds where medical modality fails. However, there is lot of scope for improvement. So more research should happen in this field so that our aim will shift from "any repigmentation" to "complete and normal repigmentation" and we can achieve a scar less healing of those "bruised souls".

摘要

白癜风是一种常见的色素障碍性疾病,会给患者带来巨大的心理社会影响。就其发病机制和治疗管理而言,这种疾病仍然是一个谜。尽管有多种治疗方法,但到目前为止,没有一种方法能解决病因。手术治疗已经有了很大的发展,并为稳定型白癜风带来了一线希望。主要目的是回顾各种可用的手术方法,并着眼于里程碑,努力寻找白癜风手术的“为什么、何时、谁和如何”的答案。本文基于对白癜风各种手术治疗的文献复习,以及作者在这一特定领域的经验。此外,作者还试图探讨影响白癜风手术效果的因素。白癜风手术的结果取决于患者的选择、对这种疾病及其奥秘的正确认识、对手术的专业知识以及对患者护理的奉献精神。可以肯定的是,许多人会选择手术方法,希望它能在医学方法失败的地方取得成功。然而,还有很大的改进空间。因此,应该在这一领域进行更多的研究,以便我们的目标将从“任何复色”转变为“完全和正常的复色”,我们可以实现那些“受伤灵魂”的无疤痕愈合。

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1
Vitiligo surgery: its evolution as a definite treatment in the stable vitiligo.白癜风手术:在稳定期白癜风中作为一种明确治疗方法的演变。
G Ital Dermatol Venereol. 2010 Feb;145(1):79-88.
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Long-term results of 2-mm punch grafting in patients with vitiligo vulgaris and segmental vitiligo: effect of disease activity.寻常型白癜风和节段型白癜风患者 2mm 打孔移植的长期疗效:疾病活动度的影响。
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Melanocyte-keratinocyte transplantation procedure in the treatment of vitiligo: the experience of an academic medical center in the United States.黑素细胞-角质形成细胞移植术治疗白癜风:美国一家学术医疗中心的经验。
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Repigmentation of vitiligo with punch grafting and narrow-band UV-B (311 nm)--a prospective study.采用钻孔移植术和窄谱中波紫外线(311nm)治疗白癜风复色的前瞻性研究
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Smashed skin grafting or smash grafting - a novel method of vitiligo surgery.削痂植皮术或磨皮移植术——一种新型的白癜风手术方法。
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引用本文的文献

1
Combination of Follicular and Epidermal Cell Suspension as a Novel Surgical Approach in Difficult-to-Treat Vitiligo: A Randomized Clinical Trial.毛囊细胞和表皮细胞混悬液移植治疗复色困难型白癜风的临床随机对照研究
JAMA Dermatol. 2018 Mar 1;154(3):301-308. doi: 10.1001/jamadermatol.2017.5795.